Eugenol

Eugenol

SCHEMBL21623969

C=CCc1ccc(O)c(OC)c1.C=CO.CCOCC

nearest known ligand 0.80

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPM8 Q7Z2W7 7/20 0.80
ALDH1A1 P00352 5/20 0.80
ALOX5 P09917 2/20 0.80
PTGS1 P23219 2/20 0.80
CYP3A4 P08684 1/20 0.80
AR P10275 1/20 0.80
GABRA1 P14867 3/20 0.59
GABRB2 P47870 3/20 0.59
PPARG P37231 2/20 0.58
PPARD Q03181 2/20 0.58
PPARA Q07869 1/20 0.58
SMN1; SMN2 Q16637 2/20 0.56
TSHR P16473 2/20 0.56
NPC1 O15118 1/20 0.56
TP53 P04637 1/20 0.56
RAB9A P51151 1/20 0.56
CNR2 P34972 2/20 0.52
TRPA1 O75762 1/20 0.52
KDM4E B2RXH2 2/20 0.50
MEN1 O00255 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Eugenol SCHEMBL12503523 0.97 TRPM8 (0.85) TRPM8ALDH1A1ALOX5PTGS1CYP3A4
Eugenol SCHEMBL357017 0.97 TRPM8 (0.85) TRPM8ALDH1A1ALOX5PTGS1CYP3A4
Eugenol SCHEMBL28163009 0.90 ALDH1A1 (0.93) TRPM8ALDH1A1ALOX5PTGS1CYP3A4
Eugenol SCHEMBL788240 0.89 ALDH1A1 (1.00) TRPM8ALDH1A1ALOX5PTGS1CYP3A4
Eugenol SCHEMBL29364978 0.89 ALDH1A1 (1.00) TRPM8ALDH1A1ALOX5PTGS1CYP3A4
Eugenol SCHEMBL20361 0.89 ALDH1A1 (1.00) TRPM8ALDH1A1ALOX5PTGS1CYP3A4
Eugenol SCHEMBL29126189 0.89 ALDH1A1 (1.00) TRPM8ALDH1A1ALOX5PTGS1CYP3A4
Eugenol SCHEMBL27521002 0.88 TRPM8 (0.90) TRPM8ALDH1A1ALOX5PTGS1CYP3A4
Eugenol SCHEMBL662388 0.88 TRPM8 (0.90) TRPM8ALDH1A1ALOX5PTGS1CYP3A4
Eugenol SCHEMBL25377864 0.88 ALDH1A1 (0.97) TRPM8ALDH1A1ALOX5PTGS1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3824060-A1 SOLID FRAGRANCE-CONTAINING COMPOSITION Henkel AG & Co. KGaA (DE) 2021-05-26 EP disclosed
WO-2020015878-A1 SOLID FRAGRANCE-CONTAINING COMPOSITION HENKEL AG & CO. KGAA (DE) 2020-01-23 WO disclosed