Eugenol

Eugenol

SCHEMBL357017

C=CCc1ccc(O)c(OC)c1.CCOCC

nearest known ligand 0.85

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPM8 Q7Z2W7 7/20 0.85
ALDH1A1 P00352 5/20 0.85
ALOX5 P09917 2/20 0.85
PTGS1 P23219 2/20 0.85
CYP3A4 P08684 1/20 0.85
AR P10275 1/20 0.85
GABRA1 P14867 3/20 0.62
GABRB2 P47870 3/20 0.62
PPARG P37231 2/20 0.61
PPARD Q03181 2/20 0.61
PPARA Q07869 1/20 0.61
SMN1; SMN2 Q16637 2/20 0.59
TSHR P16473 2/20 0.59
NPC1 O15118 1/20 0.59
TP53 P04637 1/20 0.59
RAB9A P51151 1/20 0.59
CNR2 P34972 2/20 0.54
TRPA1 O75762 1/20 0.54
XDH P47989 1/20 0.53
KDM4E B2RXH2 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Eugenol SCHEMBL12503523 1.00 TRPM8 (0.85) TRPM8ALDH1A1ALOX5PTGS1CYP3A4
Eugenol SCHEMBL21623969 0.97 TRPM8 (0.80) TRPM8ALDH1A1ALOX5PTGS1CYP3A4
Eugenol SCHEMBL28163009 0.92 ALDH1A1 (0.93) TRPM8ALDH1A1ALOX5PTGS1CYP3A4
Eugenol SCHEMBL788240 0.92 ALDH1A1 (1.00) TRPM8ALDH1A1ALOX5PTGS1CYP3A4
Eugenol SCHEMBL29364978 0.92 ALDH1A1 (1.00) TRPM8ALDH1A1ALOX5PTGS1CYP3A4
Eugenol SCHEMBL20361 0.92 ALDH1A1 (1.00) TRPM8ALDH1A1ALOX5PTGS1CYP3A4
Eugenol SCHEMBL29126189 0.92 ALDH1A1 (1.00) TRPM8ALDH1A1ALOX5PTGS1CYP3A4
Eugenol SCHEMBL27521002 0.91 TRPM8 (0.90) TRPM8ALDH1A1ALOX5PTGS1CYP3A4
Eugenol SCHEMBL662388 0.91 TRPM8 (0.90) TRPM8ALDH1A1ALOX5PTGS1CYP3A4
Eugenol SCHEMBL25377864 0.91 ALDH1A1 (0.97) TRPM8ALDH1A1ALOX5PTGS1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108841006-B Preparation method of bio-based epoxy resin with good deformation recovery performance 贵阳学院 2020-09-29 CN claimed
JP-1201310-A None JP disclosed
CN-115784853-B Mosquito repellent, preparation method thereof and application thereof in mosquito repellent 广东省科学院动物研究所 2023-12-12 CN disclosed
CN-115784853-A Mosquito repellent, preparation method thereof and application thereof in mosquito repelling 广东省科学院动物研究所 2023-03-14 CN disclosed
US-20220378675-A1 COMPOUNDS REDUCING MALODOUR PERCEPTION AND THE USE THEREOF CHEMCOM S.A. (BE) 2022-12-01 US disclosed
EP-4059917-A2 COMPOUNDS REDUCING MALODOUR PERCEPTION AND THE USE THEREOF ChemCom S.A. (BE) 2022-09-21 EP disclosed
US-11382848-B2 Compounds reducing malodour perception and the use thereof CHEMCOM S.A. (BE) 2022-07-12 US disclosed
US-20220125983-A1 MALODOR COUNTERACTING COMPOSITION AND AGENT AND THE USE THEREOF CHEMCOM S.A. (BE) 2022-04-28 US disclosed
EP-3965834-A1 MALODOR COUNTERACTING COMPOSITION AND AGENT AND THE USE THEREOF ChemCom S.A. (BE) 2022-03-16 EP disclosed
EP-3573944-B1 COMPOUNDS REDUCING MALODOUR PERCEPTION AND THE USE THEREOF CHEMCOM SA (BE) 2022-03-02 EP disclosed
US-20120014883-A1 Compositions Comprising Derivatives Of Essential Oil Compounds And Use In Personal Care Products THE PROCTER & GAMBLE COMPANY 2012-01-19 US disclosed
US-7557145-B2 Inhibition of the asexual reproduction of fungi by eugenol and/or derivatives thereof HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 2009-07-07 US disclosed
US-20070224250-A1 MOLD-RESISTANT CONSTRUCTION MATERIALS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 2007-09-27 US disclosed
US-20060128813-A1 Inhibition of the asexual reproduction of fungi by eugenol and/or derivatives thereof HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 2006-06-15 US disclosed
EP-0916689-B1 Silicone terpolymers with high refractive indices CROMPTON CORP (US) 2004-04-07 EP disclosed
US-6174983-B1 POLYSILOXANE POLYMERS C. K. WITCO CORPORATION 2001-01-16 US disclosed
CN-1223274-A Silicone Terpolymers with high refractive indices OSI SPECIALTIES INC (US) 1999-07-21 CN disclosed
EP-0916689-A1 Silicone terpolymers with high refractive indices WITCO CORPORATION (US) 1999-05-19 EP disclosed
EP-0321155-B1 Ethylenically-unsaturated ethers of alkenyl phenols as reactive diluents for bismaleimides AMOCO CORP (US) 1994-02-02 EP disclosed
JP-H01201310-A ETHYLENICALLY UNSATURATED ALKENYLPHENOL-ETHERS AS REACTIVE DILUENT FOR BISMALEIMIDE AMOCO CORP 1989-08-14 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11382848-B2 Compounds reducing malodour perception and the use thereof OR51E2, OR10J3, SRD5A1 TRPM8 290/4885ALDH1A1 248/4885ALOX5 464/4885
US-20070224250-A1 MOLD-RESISTANT CONSTRUCTION MATERIALS ERG28, DCXR, MGAM TRPM8 4388/4885ALDH1A1 999/4885ALOX5 1940/4885
US-20220378675-A1 COMPOUNDS REDUCING MALODOUR PERCEPTION AND THE USE THEREOF OR51E2, OR10J3, SRD5A1 TRPM8 290/4885ALDH1A1 248/4885ALOX5 464/4885
US-20060128813-A1 Inhibition of the asexual reproduction of fungi by eugenol and/or derivatives thereof ERG28, MEP1A, ETF1 TRPM8 2296/4885ALDH1A1 933/4885ALOX5 612/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.