SCHEMBL21628604

SCHEMBL21628604

CCCCc1ccc(Oc2ccc(C(N)=O)cc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 11/20 0.61
PARP15 Q460N3 3/20 0.61
ALDH1A1 P00352 1/20 0.61
KMT2A Q03164 1/20 0.61
PARP14 Q460N5 1/20 0.61
PARP16 Q8N5Y8 1/20 0.61
PARP11 Q9NR21 1/20 0.61
PARP4 Q9UKK3 1/20 0.61
OPRM1 P35372 1/20 0.55
OPRD1 P41143 1/20 0.55
OPRK1 P41145 1/20 0.55
RARB P10826 1/20 0.53
PLK1 P53350 1/20 0.53
THRA P10827 1/20 0.51
THRB P10828 1/20 0.51
S1PR1 P21453 1/20 0.51
S1PR3 Q99500 1/20 0.51
PARP3 Q9Y6F1 1/20 0.50
NPC1 O15118 1/20 0.49
RAB9A P51151 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21628724 0.95 PARP10 (0.59) PARP10PARP15ALDH1A1KMT2APARP14
SCHEMBL21628901 0.94 KMT2A (0.58) PARP10PARP15ALDH1A1KMT2APARP14
SCHEMBL21628632 0.90 PARP10 (0.66) PARP10PARP15ALDH1A1KMT2APARP14
SCHEMBL607614 0.90 RARB (0.62) ALDH1A1KMT2ARARBPLK1THRA
SCHEMBL21656831 0.85 RARB (0.73) ALDH1A1KMT2ARARBPLK1THRA
SCHEMBL15750344 0.85 RARB (0.72) ALDH1A1KMT2ARARBPLK1THRA
SCHEMBL2677626 0.84 RARB (0.64) ALDH1A1KMT2ARARBTHRATHRB
SCHEMBL351935 0.83 THRA (0.65) ALDH1A1KMT2ARARBTHRATHRB
SCHEMBL6835676 0.83 THRA (0.65) ALDH1A1KMT2ARARBTHRATHRB
SCHEMBL13617729 0.83 THRA (0.65) ALDH1A1KMT2ARARBTHRATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12600696-B2 Aromatic compounds Xeniopro GmbH (DE) 2026-04-14 US disclosed
US-20230406814-A2 NOVEL AROMATIC COMPOUNDS Xeniopro GmbH (DE) 2023-12-21 US disclosed
US-20230150923-A1 NOVEL AROMATIC COMPOUNDS Xeniopro GmbH (DE) 2023-05-18 US disclosed
US-11591289-B2 Aromatic compounds Xeniopro GmbH (DE) 2023-02-28 US disclosed
US-11591289-B2 Aromatic compounds Xeniopro GmbH (DE) 2023-02-28 US disclosed
US-20220348535-A2 NOVEL AROMATIC COMPOUNDS Xeniopro GmbH (DE) 2022-11-03 US disclosed
US-20210107863-A2 NOVEL AROMATIC COMPOUNDS Xeniopro GmbH (DE) 2021-04-15 US disclosed
US-20200031763-A1 NOVEL AROMATIC COMPOUNDS Xeniopro GmbH (DE) 2020-01-30 US disclosed
US-20200031763-A1 NOVEL AROMATIC COMPOUNDS Xeniopro GmbH (DE) 2020-01-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230150923-A1 NOVEL AROMATIC COMPOUNDS AHR, TYR, MUSK PARP10 1944/4885PARP15 2818/4885ALDH1A1 717/4885
US-20220348535-A2 NOVEL AROMATIC COMPOUNDS AHR, TYR, MUSK PARP10 1944/4885PARP15 2818/4885ALDH1A1 717/4885
US-11591289-B2 Aromatic compounds AHR, TYR, MUSK PARP10 1897/4885PARP15 2681/4885ALDH1A1 900/4885
US-20210107863-A2 NOVEL AROMATIC COMPOUNDS AHR, TYR, MUSK PARP10 1944/4885PARP15 2818/4885ALDH1A1 717/4885
US-12600696-B2 Aromatic compounds CCR1, CCRL2, AHR PARP10 3512/4885PARP15 4342/4885ALDH1A1 929/4885
US-20230406814-A2 NOVEL AROMATIC COMPOUNDS AHR, TYR, MUSK PARP10 1944/4885PARP15 2818/4885ALDH1A1 717/4885
US-20200031763-A1 NOVEL AROMATIC COMPOUNDS AHR, TYR, MUSK PARP10 1944/4885PARP15 2818/4885ALDH1A1 717/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.