SCHEMBL21628489

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21628688	0.94	ALDH1A1 (0.67)	HPGDALDH1A1SMN1; SMN2MMP13MEN1
	SCHEMBL21628904	0.94	ALDH1A1 (0.67)	HPGDALDH1A1SMN1; SMN2MMP13MEN1
	SCHEMBL21628651	0.92	ALDH1A1 (0.65)	HPGDALDH1A1SMN1; SMN2MMP13MEN1
	SCHEMBL21628738	0.92	ALDH1A1 (0.65)	HPGDALDH1A1SMN1; SMN2MMP13MEN1
	SCHEMBL21628747	0.83	SMN1; SMN2 (0.49)	HPGDALDH1A1SMN1; SMN2
	SCHEMBL21628619	0.82	ALDH1A1 (0.48)	HPGDALDH1A1SMN1; SMN2SLC6A2SLC6A4
	SCHEMBL21274803	0.80	PARP10 (0.56)	HPGDALDH1A1KMT2APARP10MAPT
	SCHEMBL744509	0.79	ESR2 (0.56)	HPGDALDH1A1SMN1; SMN2SLC6A2SLC6A4
	SCHEMBL21288239	0.79	CA1 (0.55)	HPGDALDH1A1SMN1; SMN2MEN1KMT2A
	SCHEMBL31700659	0.79	LIMK2 (0.49)	HPGDALDH1A1SMN1; SMN2USP30CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.