SCHEMBL21628688

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21628904	0.97	ALDH1A1 (0.67)	ALDH1A1SMN1; SMN2HPGDMEN1KMT2A
	SCHEMBL21628738	0.95	ALDH1A1 (0.65)	ALDH1A1SMN1; SMN2HPGDMEN1KMT2A
	SCHEMBL21628651	0.95	ALDH1A1 (0.65)	ALDH1A1SMN1; SMN2HPGDMEN1KMT2A
	SCHEMBL21628489	0.94	HPGD (0.71)	ALDH1A1SMN1; SMN2HPGDMEN1KMT2A
	SCHEMBL21628652	0.84	HRH3 (0.48)	ALDH1A1SMN1; SMN2HPGD
	SCHEMBL21628380	0.83	SLC6A2 (0.46)	ALDH1A1SMN1; SMN2HPGDPARP10GPR119
	SCHEMBL21656804	0.81	PARP10 (0.53)	ALDH1A1SMN1; SMN2MEN1KMT2ASTAT3
	SCHEMBL21656805	0.80	ALDH1A1 (0.54)	ALDH1A1SMN1; SMN2HPGDMAPTHDAC1
	SCHEMBL21628902	0.80	PARP10 (0.63)	ALDH1A1KMT2APARP10
	SCHEMBL21628888	0.79	SMN1; SMN2 (0.67)	ALDH1A1SMN1; SMN2HPGDMMP13MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.