SCHEMBL21628537

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21628474	0.87	HPGD (0.61)	MEN1KMT2ARAB9ACNR2NPC1
	SCHEMBL21628411	0.85	HDAC6 (0.47)	MEN1KMT2ARAB9AHDAC6NPC1
	SCHEMBL21628401	0.84	HDAC6 (0.48)	MEN1KMT2ARAB9AHDAC6CNR2
	SCHEMBL19362904	0.84	MEN1 (0.55)	MEN1KMT2ARAB9ANPC1SERPINE1
	SCHEMBL23210638	0.83	HIF1A (0.64)	MEN1KMT2ARAB9ACNR2NPC1
	SCHEMBL21628735	0.82	KMT2A (0.61)	MEN1KMT2ARAB9ANPC1HIF1A
	SCHEMBL27845478	0.81	LMNA (0.61)	MEN1KMT2ARAB9ANPC1HIF1A
	SCHEMBL21657041	0.79	HDAC6 (0.43)	MEN1KMT2ARAB9AHDAC6HIF1A
	SCHEMBL21628884	0.79	ALDH1A1 (0.61)	MEN1KMT2ARAB9ANPC1HIF1A
	SCHEMBL21752960	0.79	MEN1 (0.50)	MEN1KMT2ARAB9ANPC1HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.