SCHEMBL21628561

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21628786	0.95	PARP10 (0.59)	PARP10PARP15PARP14PARP4ALDH1A1
	SCHEMBL21628746	0.90	PARP10 (0.66)	PARP10PARP15PARP14PARP4ALDH1A1
	SCHEMBL21656835	0.85	PARP15 (0.51)	PARP10PARP15ALDH1A1CA1CA2
	SCHEMBL21628736	0.83	PARP10 (0.51)	PARP10PARP15PARP14PARP4ALDH1A1
	SCHEMBL21628495	0.83	LMNA (0.52)	—
	SCHEMBL29920899	0.83	LMNA (0.52)	—
	SCHEMBL21628511	0.83	PARP10 (0.66)	PARP10PARP15PARP14PARP4ALDH1A1
	SCHEMBL9388045	0.83	PARP10 (0.70)	PARP10PARP15PARP14PARP4ALDH1A1
	SCHEMBL21628838	0.83	ALOX15 (0.49)	CA1CA2TSHR
	SCHEMBL21656806	0.81	LMNA (0.56)	ALDH1A1KMT2ACA1CA2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.