SCHEMBL21628563

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21628595	0.88	PARP10 (0.51)	MAPK1HDAC8HDAC6
	SCHEMBL21628887	0.87	USP2 (0.44)	LMNAMAPK1HTTRAB9AHDAC8
	SCHEMBL21628545	0.86	CA12 (0.43)	LMNAMAPK1HDAC8HDAC6
	SCHEMBL21628568	0.86	SLC6A2 (0.47)	HTTS1PR2PTGER4PTGER2HDAC8
	SCHEMBL21628816	0.86	HDAC6 (0.59)	HDAC8HDAC6
	SCHEMBL21656770	0.86	SLC6A2 (0.49)	LPAR1LPAR5S1PR2HDAC8HDAC6
	SCHEMBL21628711	0.85	LMNA (0.56)	LMNAMAPK1HTTRAB9ATTR
	SCHEMBL21628551	0.82	LMNA (0.56)	LMNAMAPK1HTTRAB9ATTR
	SCHEMBL21656832	0.81	SRD5A2 (0.58)	MAPK1RAB9AHDAC8HDAC6
	SCHEMBL21274603	0.80	LMNA (0.60)	LMNAMAPK1HTTRAB9ATTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.