SCHEMBL21628595

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21628563	0.88	LMNA (0.52)	HDAC8HDAC6MAPK1
	SCHEMBL21628887	0.86	USP2 (0.44)	ALDH1A1KMT2AHDAC8HDAC6MAPK1
	SCHEMBL21628795	0.85	PARP10 (0.55)	PARP10OPRK1OPRM1OPRD1SLC6A4
	SCHEMBL21656770	0.85	SLC6A2 (0.49)	SLC6A4SLC6A2ALDH1A1HDAC8HDAC6
	SCHEMBL21628816	0.85	HDAC6 (0.59)	OPRK1OPRM1HDAC8HDAC6
	SCHEMBL21628545	0.85	CA12 (0.43)	KMT2AHDAC8HDAC6MAPK1
	SCHEMBL21628568	0.85	SLC6A2 (0.47)	SLC6A4SLC6A2HDAC8HDAC6
	SCHEMBL21628562	0.83	PARP10 (0.55)	PARP10OPRK1OPRM1OPRD1SLC6A4
	SCHEMBL21628742	0.82	PARP10 (0.63)	PARP10PARP15PARP14ALDH1A1KMT2A
	SCHEMBL21628730	0.81	PARP10 (0.59)	PARP10OPRK1OPRM1OPRD1SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.