SCHEMBL21628659

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21628642	0.91	MAOB (0.48)	MAOBCYP2C9CYP2C19CYP1A2POLB
	SCHEMBL14656159	0.89	P2RY12 (0.44)	MAOBCYP2C9CYP2C19CYP1A2POLB
	SCHEMBL21628788	0.88	S1PR1 (0.48)	MAOBCYP2C9CYP2C19CYP1A2POLB
	SCHEMBL21628761	0.88	MAOB (0.46)	MAOBCYP2C9CYP2C19CYP1A2POLB
	SCHEMBL20827025	0.88	MAOB (0.47)	MAOBCYP2C9CYP2C19CYP1A2POLB
	SCHEMBL21628567	0.88	MAOB (0.57)	MAOBCYP2C9CYP2C19CYP1A2POLB
	SCHEMBL21628677	0.87	S1PR1 (0.45)	MAOBCYP2C9CYP2C19CYP1A2POLB
	SCHEMBL21628625	0.87	TDP1 (0.46)	L3MBTL1LMNAALDH1A1TDP1MAPT
	SCHEMBL21628869	0.86	MAOB (0.40)	MAOBCYP2C9CYP2C19CYP1A2POLB
	SCHEMBL21628397	0.86	MAOB (0.48)	MAOBCYP2C9CYP2C19CYP1A2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.