SCHEMBL21628642

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21628761	0.92	MAOB (0.46)	MAOBP2RX3CYP1A2POLBCYP2C9
	SCHEMBL21628659	0.91	MAOB (0.52)	MAOBP2RX3CYP1A2POLBCYP2C9
	SCHEMBL21628715	0.90	MAOB (0.44)	MAOBP2RX3CYP1A2POLBCYP2C9
	SCHEMBL21628482	0.89	VNN1 (0.44)	MAOBP2RX3L3MBTL1LMNAPTGER4
	SCHEMBL21628741	0.89	PLA2G4A (0.45)	MAOBP2RX3MAPT
	SCHEMBL21628399	0.88	PLA2G4A (0.46)	MAOBP2RX3
	SCHEMBL14656159	0.88	P2RY12 (0.44)	MAOBP2RX3CYP1A2POLBCYP2C9
	SCHEMBL21628506	0.87	RXRA (0.49)	P2RX3L3MBTL1ALDH1A1PTGER4MAPT
	SCHEMBL21628788	0.87	S1PR1 (0.48)	MAOBP2RX3CYP1A2POLBCYP2C9
	SCHEMBL20827025	0.87	MAOB (0.47)	MAOBP2RX3CYP1A2POLBCYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.