SCHEMBL21628869

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21628453	0.96	MAPT (0.43)	MAOBMAPTLMNACYP1A2POLB
	SCHEMBL21628556	0.96	MAPT (0.41)	MAOBMAPTLMNACYP1A2POLB
	SCHEMBL21628597	0.95	ALDH1A1 (0.45)	MAOBMAPTLMNACYP1A2POLB
	SCHEMBL21628680	0.95	ALDH1A1 (0.45)	MAOBMAPTLMNACYP1A2POLB
	SCHEMBL21628578	0.87	ALOX5AP (0.40)	LMNATSHRMAPK1NPSR1ACACB
	SCHEMBL21628659	0.86	MAOB (0.52)	MAOBMAPTLMNACYP1A2POLB
	SCHEMBL21628642	0.85	MAOB (0.48)	MAOBMAPTLMNACYP1A2POLB
	SCHEMBL21656920	0.85	SLC6A3 (0.37)	MAOBLMNACYP1A2POLBCYP2C9
	SCHEMBL21628617	0.83	MRGPRX4 (0.46)	—
	SCHEMBL21628687	0.83	ALOX5AP (0.43)	MAPTLMNAALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.