SCHEMBL21628692

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21628820	0.95	HPGD (0.67)	HTTHPGDTSHRSMN1; SMN2MMP13
	SCHEMBL21656697	0.89	HPGD (0.71)	HTTHPGDTSHRSMN1; SMN2MMP13
	SCHEMBL21628460	0.87	ALOX15 (0.47)	HTTHPGDTSHRSMN1; SMN2MMP13
	SCHEMBL21628471	0.86	SLC6A2 (0.48)	HTTHPGDTSHRSMN1; SMN2MMP13
	SCHEMBL21628509	0.86	LMNA (0.54)	HTTHPGDTSHRSMN1; SMN2MMP13
	SCHEMBL21656474	0.85	LMNA (0.54)	HTTHPGDTSHRSMN1; SMN2MAPT
	SCHEMBL21656836	0.83	PARP15 (0.50)	TSHRMAPK14RAB9A
	SCHEMBL21628623	0.83	HPGD (0.71)	HTTHPGDTSHRSMN1; SMN2MMP13
	SCHEMBL21628855	0.83	HPGD (0.76)	HTTHPGDTSHRSMN1; SMN2MMP13
	SCHEMBL21628838	0.82	ALOX15 (0.49)	HTTHPGDTSHRSMN1; SMN2MMP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.