SCHEMBL21628699

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21628418	1.00	PARP10 (0.45)	PARP10SIRT2SIRT1SIRT3PARP14
	SCHEMBL21628434	0.99	PARP10 (0.46)	PARP10SIRT2SIRT1SIRT3PARP14
	SCHEMBL21628753	0.96	PARP10 (0.46)	PARP10SIRT2SIRT1SIRT3PARP14
	SCHEMBL21628849	0.94	PARP10 (0.47)	PARP10SIRT2SIRT1SIRT3PARP14
	SCHEMBL20482060	0.89	KMT2A (0.45)	ALOX5APFEN1HAO1KDM4EGLA
	SCHEMBL21628889	0.89	KMT2A (0.45)	ALOX5APFEN1HAO1KDM4EGLA
	SCHEMBL21628737	0.88	KMT2A (0.43)	ALOX5APFEN1HAO1KDM4EGLA
	SCHEMBL21628383	0.86	SMN1; SMN2 (0.42)	ALOX5APFEN1HAO1KDM4EGLA
	SCHEMBL20482263	0.86	HDAC6 (0.51)	HAO1KMT2A
	SCHEMBL21628405	0.86	FEN1 (0.42)	PARP10ALOX5APFEN1HAO1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.