SCHEMBL21628849

SCHEMBL21628849

NC(=O)c1cnc(Oc2ccc(C3CC3)cc2)c(F)c1

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 7/20 0.47
PARP14 Q460N5 4/20 0.44
DGAT1 O75907 1/20 0.41
BTK Q06187 5/20 0.39
FEN1 P39748 2/20 0.39
CYP2C9 P11712 1/20 0.39
ALOX5AP P20292 1/20 0.39
EGFR P00533 2/20 0.38
HPGDS O60760 1/20 0.38
MRGPRX4 Q96LA9 1/20 0.38
ALDH1A1 P00352 1/20 0.37
KMT2A Q03164 1/20 0.37
PARP15 Q460N3 1/20 0.37
PARP16 Q8N5Y8 1/20 0.37
PARP11 Q9NR21 1/20 0.37
PARP4 Q9UKK3 1/20 0.37
SIRT2 Q8IXJ6 1/20 0.37
SIRT1 Q96EB6 1/20 0.37
SIRT3 Q9NTG7 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21628753 0.95 PARP10 (0.46) PARP10PARP14DGAT1BTKFEN1
SCHEMBL21628434 0.95 PARP10 (0.46) PARP10PARP14BTKFEN1ALOX5AP
SCHEMBL21628699 0.94 PARP10 (0.45) PARP10PARP14BTKFEN1ALOX5AP
SCHEMBL21628418 0.94 PARP10 (0.45) PARP10PARP14BTKFEN1ALOX5AP
SCHEMBL21628617 0.89 MRGPRX4 (0.46) PARP10FEN1ALOX5APMRGPRX4
SCHEMBL21628578 0.85 ALOX5AP (0.40) PARP10FEN1ALOX5APMRGPRX4
SCHEMBL21628554 0.85 HDAC6 (0.45)
SCHEMBL21628762 0.84 CSF1R (0.43) HPGDS
SCHEMBL21628912 0.84 SMN1; SMN2 (0.41) PARP10PARP14MRGPRX4ALDH1A1
SCHEMBL21628737 0.84 KMT2A (0.43) FEN1ALOX5APMRGPRX4ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12600696-B2 Aromatic compounds Xeniopro GmbH (DE) 2026-04-14 US disclosed
US-20230406814-A2 NOVEL AROMATIC COMPOUNDS Xeniopro GmbH (DE) 2023-12-21 US disclosed
US-20230150923-A1 NOVEL AROMATIC COMPOUNDS Xeniopro GmbH (DE) 2023-05-18 US disclosed
US-11591289-B2 Aromatic compounds Xeniopro GmbH (DE) 2023-02-28 US disclosed
US-11591289-B2 Aromatic compounds Xeniopro GmbH (DE) 2023-02-28 US disclosed
US-20220348535-A2 NOVEL AROMATIC COMPOUNDS Xeniopro GmbH (DE) 2022-11-03 US disclosed
US-20210107863-A2 NOVEL AROMATIC COMPOUNDS Xeniopro GmbH (DE) 2021-04-15 US disclosed
US-20200031763-A1 NOVEL AROMATIC COMPOUNDS Xeniopro GmbH (DE) 2020-01-30 US disclosed
US-20200031763-A1 NOVEL AROMATIC COMPOUNDS Xeniopro GmbH (DE) 2020-01-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230150923-A1 NOVEL AROMATIC COMPOUNDS AHR, TYR, MUSK PARP10 1944/4885PARP14 2599/4885DGAT1 4780/4885
US-20220348535-A2 NOVEL AROMATIC COMPOUNDS AHR, TYR, MUSK PARP10 1944/4885PARP14 2599/4885DGAT1 4780/4885
US-11591289-B2 Aromatic compounds AHR, TYR, MUSK PARP10 1897/4885PARP14 2483/4885DGAT1 4770/4885
US-20210107863-A2 NOVEL AROMATIC COMPOUNDS AHR, TYR, MUSK PARP10 1944/4885PARP14 2599/4885DGAT1 4780/4885
US-12600696-B2 Aromatic compounds CCR1, CCRL2, AHR PARP10 3512/4885PARP14 3870/4885DGAT1 3876/4885
US-20230406814-A2 NOVEL AROMATIC COMPOUNDS AHR, TYR, MUSK PARP10 1944/4885PARP14 2599/4885DGAT1 4780/4885
US-20200031763-A1 NOVEL AROMATIC COMPOUNDS AHR, TYR, MUSK PARP10 1944/4885PARP14 2599/4885DGAT1 4780/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.