SCHEMBL21628720

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21628711	0.86	LMNA (0.56)	RAB9APTGER4PTGER2SCN8ASCN10A
	SCHEMBL21657019	0.86	ALDH1A1 (0.45)	USP2RAB9AMAPTALDH1A1HPGD
	SCHEMBL21628710	0.86	NPC1 (0.44)	RAB9AMAPTNPC1LMNACA1
	SCHEMBL21628887	0.86	USP2 (0.44)	USP2RAB9AMAPTALDH1A1HPGD
	SCHEMBL29921049	0.85	HDAC6 (0.49)	PTGER4PTGER2SCN8ASCN10AKCNQ3
	SCHEMBL21628789	0.85	HDAC6 (0.49)	PTGER4PTGER2SCN8ASCN10AKCNQ3
	SCHEMBL21628430	0.85	SMN1; SMN2 (0.50)	RAB9ANPC1ALDH1A1HPGDPTGER4
	SCHEMBL21628795	0.85	PARP10 (0.55)	ALDH1A1PTGER4PTGER2KMT2APARP10
	SCHEMBL21628782	0.85	TDP1 (0.54)	USP2RAB9AMAPTALDH1A1HPGD
	SCHEMBL21628662	0.82	KMT2A (0.48)	USP2RAB9AMAPTNPC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.