SCHEMBL21628792

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20032263	0.90	HDAC8 (0.73)	HPGDTSHRHTTSMN1; SMN2MMP13
	SCHEMBL21628751	0.88	HDAC6 (0.81)	HPGDTSHRHTTSMN1; SMN2MMP13
	SCHEMBL18713762	0.85	HDAC8 (0.67)	HPGDTSHRHTTSMN1; SMN2HDAC8
	SCHEMBL21657001	0.84	OPRM1 (0.55)	HPGDTSHRHTTSMN1; SMN2MMP13
	SCHEMBL13184545	0.83	HPGD (1.00)	HPGDTSHRHTTSMN1; SMN2MMP13
	SCHEMBL21628568	0.83	SLC6A2 (0.47)	HPGDTSHRHTTSMN1; SMN2MMP13
	SCHEMBL21656844	0.83	HDAC8 (0.54)	HPGDSMN1; SMN2HDAC8HDAC6
	SCHEMBL21656832	0.82	SRD5A2 (0.58)	HPGDTSHRHDAC8HDAC6
	SCHEMBL20482354	0.82	SMN1; SMN2 (0.76)	HPGDTSHRHTTSMN1; SMN2MMP13
	SCHEMBL21628742	0.81	PARP10 (0.63)	HPGDHDAC8HDAC6MMP14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.