SCHEMBL21628751

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21628792	0.88	HPGD (0.69)	HDAC6HDAC8HPGDTSHRHTT
	SCHEMBL21628402	0.84	HDAC6 (0.61)	HDAC6HDAC8HDAC1HDAC2HDAC3
	SCHEMBL21628816	0.83	HDAC6 (0.59)	HDAC6HDAC8HDAC1
	SCHEMBL21656844	0.83	HDAC8 (0.54)	HDAC6HDAC8CA1CA2HPGD
	SCHEMBL21656832	0.82	SRD5A2 (0.58)	HDAC6HDAC8CA1CA2HPGD
	SCHEMBL21628436	0.82	HDAC6 (0.59)	HDAC6HDAC8CA1CA2HDAC1
	SCHEMBL21628742	0.81	PARP10 (0.63)	HDAC6HDAC8CA1CA2HPGD
	SCHEMBL21628685	0.79	PLK1 (0.58)	HDAC6HDAC8CA1CA2HDAC1
	SCHEMBL24293854	0.78	HDAC8 (0.49)	HDAC6HDAC8HPGDHTTALOX15
	SCHEMBL21656852	0.78	CA12 (0.53)	HDAC6HDAC8CA1CA2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.