Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.38 |
| ▸ | CHRNB3 | Q05901 | 3/20 | 0.38 |
| ▸ | CHRNA6 | Q15825 | 3/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29117225 | 0.94 | ALDH1A1 (0.50) | HPGDALDH1A1TSHRCHRNB2CHRNA3 | |
| SCHEMBL29117223 | 0.94 | ALDH1A1 (0.50) | HPGDALDH1A1TSHRCHRNB2CHRNA3 | |
| SCHEMBL28523199 | 0.90 | HPGD (0.42) | HPGDALDH1A1HTTTSHRATM | |
| SCHEMBL28523201 | 0.90 | HPGD (0.42) | HPGDALDH1A1HTTTSHRATM | |
| SCHEMBL28523191 | 0.84 | ATM (0.42) | ALDH1A1HTTATMCHRNB2CHRNA3 | |
| SCHEMBL28999414 | 0.81 | ATM (0.43) | ALDH1A1ATMSMN1; SMN2NAMPT | |
| SCHEMBL27831959 | 0.80 | CHRNB2 (0.46) | HPGDALDH1A1TSHRATMCHRNB2 | |
| SCHEMBL28669901 | 0.79 | HPGD (0.50) | HPGDALDH1A1HTTTSHRATM | |
| SCHEMBL9829905 | 0.79 | TPSAB1 (0.38) | ATMCHRNB2CHRNA3CHRNA4SMN1; SMN2 | |
| SCHEMBL20240601 | 0.78 | BTK (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020022787-A1 | NOVEL IMIDAZOLE DERIVATIVE HAVING JNK INHIBITORY ACTIVITY, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 삼진제약주식회사 | 2020-01-30 | — | — | WO | disclosed |