Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT1 | P54687 | 17/20 | 0.42 |
| ▸ | BCAT2 | O15382 | 15/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27307569 | 1.00 | BCAT1 (0.42) | BCAT1BCAT2TSHRHSD17B10MAPT | |
| SCHEMBL29692316 | 1.00 | BCAT1 (0.42) | BCAT1BCAT2TSHRHSD17B10MAPT | |
| SCHEMBL30678042 | 1.00 | BCAT1 (0.42) | BCAT1BCAT2TSHRHSD17B10MAPT | |
| SCHEMBL23698930 | 0.91 | BCAT1 (0.46) | BCAT1BCAT2HSD17B10ALDH1A1TDP1 | |
| SCHEMBL26041114 | 0.90 | HSD17B10 (0.37) | TSHRHSD17B10MAPTALDH1A1TDP1 | |
| SCHEMBL21635546 | 0.88 | BCAT1 (0.41) | BCAT1BCAT2ALDH1A1 | |
| SCHEMBL25061754 | 0.88 | BCAT1 (0.38) | BCAT1BCAT2TSHRHSD17B10MAPT | |
| SCHEMBL21653880 | 0.86 | BCAT1 (0.40) | BCAT1BCAT2TSHRHSD17B10MAPT | |
| SCHEMBL21816909 | 0.85 | BCAT1 (0.40) | BCAT1BCAT2TSHRHSD17B10MAPT | |
| SCHEMBL21653745 | 0.84 | CA1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3858829-B1 | METHOD FOR PREPARING ISOXAZOLINE-CONTAINING URACIL COMPOUND BY METHYLATION | SHENYANG SINOCHEM AGROCHEMICALS R & D CO LTD (CN) | 2024-05-01 | — | — | EP | disclosed |
| CN-113880774-B | Preparation method of phenyl isoxazoline compound | 沈阳中化农药化工研发有限公司 | 2023-12-08 | — | — | CN | disclosed |
| US-20230303545-A1 | PREPARATION METHOD OF PHENYLISOXAZOLINE COMPOUND | SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD. (CN) | 2023-09-28 | — | — | US | disclosed |
| US-20230265084-A1 | METHOD FOR PREPARING INTERMEDIATE OF URACIL COMPOUND CONTAINING ISOXAZOLINE | SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD. (CN) | 2023-08-24 | — | — | US | disclosed |
| EP-4177251-A1 | METHOD FOR PREPARING ISOXAZOLINE-CONTAINING URACIL COMPOUND INTERMEDIATES | Shenyang Sinochem Agrochemicals R & D Co., Ltd. (CN) | 2023-05-10 | — | — | EP | disclosed |
| CN-110964001-B | Method for preparing isoxazoline-containing uracil compound through methylation | 沈阳中化农药化工研发有限公司 | 2022-07-22 | — | — | CN | disclosed |
| WO-2022002117-A1 | METHOD FOR PREPARING ISOXAZOLINE-CONTAINING URACIL COMPOUND INTERMEDIATES | 沈阳中化农药化工研发有限公司 | 2022-01-06 | — | — | WO | disclosed |
| CN-113880774-A | Preparation method of phenyl isoxazoline compound | 沈阳中化农药化工研发有限公司 | 2022-01-04 | — | — | CN | disclosed |
| EP-3858829-A1 | METHOD FOR PREPARING ISOXAZOLINE-CONTAINING URACIL COMPOUND BY METHYLATION | Shenyang Sinochem Agrochemicals R & D Co., Ltd. (CN) | 2021-08-04 | — | — | EP | disclosed |
| CN-105753853-B | Isoxazoline-containing uracil compound and application thereof | 沈阳中化农药化工研发有限公司 | 2020-08-04 | — | — | CN | disclosed |
| CN-110964001-A | Method for preparing isoxazoline-containing uracil compounds through methylation | 沈阳中化农药化工研发有限公司 | 2020-04-07 | — | — | CN | disclosed |
| CN-106536517-B | Isoxazoline-containing uracil compound and application thereof | 沈阳中化农药化工研发有限公司 | 2020-03-17 | — | — | CN | disclosed |
| US-10550111-B2 | Pyrimidine urea compound containing isoxazolines and use thereof | SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD. (CN) | 2020-02-04 | — | — | US | disclosed |
| US-10550111-B2 | Pyrimidine urea compound containing isoxazolines and use thereof | SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD. (CN) | 2020-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230265084-A1 | METHOD FOR PREPARING INTERMEDIATE OF URACIL COMPOUND CONTAINING ISOXAZOLINE | UNG, IMPDH1, PNP | BCAT1 290/4885BCAT2 457/4885TSHR 628/4885 |
| US-20230303545-A1 | PREPARATION METHOD OF PHENYLISOXAZOLINE COMPOUND | UMPS, UGT1A7, UGT2B7 | BCAT1 1141/4885BCAT2 830/4885TSHR 2604/4885 |
| US-10550111-B2 | Pyrimidine urea compound containing isoxazolines and use thereof | DDX6, OAT, DHX36 | BCAT1 2789/4885BCAT2 2976/4885TSHR 4467/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.