Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25166724 | 0.84 | FFAR4 (0.35) | CA1CA2KDM4EF10 | |
| SCHEMBL22714398 | 0.83 | CA1 (0.33) | CA1CA2KDM4EF10HPGD | |
| SCHEMBL28363145 | 0.81 | SSTR5 (0.33) | CA1CA2KDM4EF10HPGD | |
| SCHEMBL21635540 | 0.80 | ESPL1 (0.37) | CA1CA2CRBN | |
| SCHEMBL21653847 | 0.80 | KDM1A (0.37) | CA1CA2KDM4EF10CRBN | |
| SCHEMBL28570370 | 0.79 | CA1 (0.44) | CA1CA2KDM4EF10 | |
| SCHEMBL22714376 | 0.79 | CA1 (0.44) | CA1CA2F10CRBN | |
| SCHEMBL21635545 | 0.79 | CA1 (0.44) | CA1CA2KDM4EF10 | |
| SCHEMBL30122767 | 0.79 | CA1 (0.44) | CA1CA2KDM4EF10 | |
| SCHEMBL30122895 | 0.79 | CA1 (0.44) | CA1CA2KDM4EF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105753853-B | Isoxazoline-containing uracil compound and application thereof | 沈阳中化农药化工研发有限公司 | 2020-08-04 | — | — | CN | disclosed |
| CN-106536517-B | Isoxazoline-containing uracil compound and application thereof | 沈阳中化农药化工研发有限公司 | 2020-03-17 | — | — | CN | disclosed |
| US-10550111-B2 | Pyrimidine urea compound containing isoxazolines and use thereof | SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD. (CN) | 2020-02-04 | — | — | US | disclosed |
| US-10550111-B2 | Pyrimidine urea compound containing isoxazolines and use thereof | SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD. (CN) | 2020-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10550111-B2 | Pyrimidine urea compound containing isoxazolines and use thereof | DDX6, OAT, DHX36 | CA1 3124/4885CA2 3606/4885KDM4E 1077/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.