Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | PLK1 | P53350 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | RXRA | P19793 | 2/20 | 0.48 |
| ▸ | RXRB | P28702 | 2/20 | 0.48 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.48 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.44 |
| ▸ | LPL | P06858 | 1/20 | 0.44 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.44 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL9816065 | 0.84 | ALDH1A1 (0.71) | ALDH1A1PLK1SMN1; SMN2TDP1RXRA | |
| Bicarbonate SCHEMBL29051240 | 0.84 | ALDH1A1 (0.71) | ALDH1A1PLK1SMN1; SMN2TDP1RXRA | |
| SCHEMBL2935942 | 0.82 | ALDH1A1 (0.70) | ALDH1A1PLK1SMN1; SMN2TDP1RXRA | |
| SCHEMBL6259079 | 0.82 | ALDH1A1 (0.70) | ALDH1A1PLK1SMN1; SMN2TDP1RXRA | |
| SCHEMBL4396484 | 0.81 | PLK1 (0.62) | ALDH1A1PLK1TDP1MAPTGAA | |
| SCHEMBL19901 | 0.80 | ALDH1A1 (1.00) | ALDH1A1PLK1SMN1; SMN2TDP1RXRA | |
| SCHEMBL1330795 | 0.80 | ALDH1A1 (1.00) | ALDH1A1PLK1SMN1; SMN2TDP1RXRA | |
| SCHEMBL1330335 | 0.80 | ALDH1A1 (1.00) | ALDH1A1PLK1SMN1; SMN2TDP1RXRA | |
| SCHEMBL334751 | 0.80 | KMT2A (0.70) | ALDH1A1PLK1SMN1; SMN2TDP1RXRA | |
| SCHEMBL13683317 | 0.80 | ALDH1A1 (0.67) | ALDH1A1PLK1SMN1; SMN2TDP1RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110184173-A1 | Pyripyropene Derivatives Having An ACAT2-Inhibiting Activity | THE KITASATO INSTITUTE (JP) | 2011-07-28 | — | — | US | claimed |
| EP-2228376-A1 | PYRIPYROPENE DERIVATIVE HAVING ACAT2-INHIBITING ACTIVITY | The Kitasato Institute (JP) | 2010-09-15 | — | — | EP | claimed |
| US-6765023-B2 | SUCH AS 3-((3-(3-TRIFLUOROMETHOXYPHENOXY)PHENYL)((3-(1,1,2,2-TETRAFLUOROETHOXY) -PHENYL)METHYL) AMINO)-1,1,1-TRIFLUORO-2-PROPANOL FOR TREATING CARDIOVASCULAR DISORDERS AND DYSLIPIDEMIA | PFIZER, INC. | 2004-07-20 | — | — | US | claimed |
| US-20040116297-A1 | Use of polyprenol and its derivatives for facilitating growth of plants | KWON SEONG-RYONG (KR) | 2004-06-17 | — | — | US | claimed |
| CN-114920744-B | Non-covalent BTK kinase inhibitor and biological application thereof | 中国药科大学 | 2024-05-07 | — | — | CN | disclosed |
| US-20240021012-A1 | FINGERPRINT RECOGNITION SENSOR AND OPTICAL ELEMENT | FUJIFILM CORPORATION (JP) | 2024-01-18 | — | — | US | disclosed |
| CN-116375715-A | Compound serving as non-covalent BTK kinase inhibitor and biological application thereof | 中国药科大学 | 2023-07-04 | — | — | CN | disclosed |
| WO-2022210850-A1 | FINGERPRINT AUTHENTICATION SENSOR, AND OPTICAL ELEMENT | 富士フイルム株式会社 | 2022-10-06 | — | — | WO | disclosed |
| EP-2478981-B1 | SILVER-(CONJUGATED COMPOUND) COMPLEX | SUMITOMO CHEMICAL CO (JP) | 2020-12-23 | — | — | EP | disclosed |
| US-9704612-B2 | Composition of silver-conjugated compound composite | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-07-11 | — | — | US | disclosed |
| US-9412487-B2 | Silver-(conjugated compound) composite | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-08-09 | — | — | US | disclosed |
| EP-2228376-B1 | PYRIPYROPENE DERIVATIVE HAVING ACAT2-INHIBITING ACTIVITY | KITASATO INST (JP) | 2015-06-03 | — | — | EP | disclosed |
| US-5012018-A | Extending polyisoprene chain using copper catalyst | KURARAY CO., LTD. (JP) | 1991-04-30 | — | — | US | disclosed |
| US-4886904-A | CONTAINING CIS AND TRANS ISOPRENE UNITS | KURARAY CO., LTD. (JP) | 1989-12-12 | — | — | US | disclosed |
| EP-0180188-A2 | A composition for increasing the anti-cancer activity of an anti-cancer compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-05-07 | — | — | EP | disclosed |
| EP-0054753-B1 | POLYPRENYL COMPOSITION OR COMPOUNDS AND PROCESS FOR THE PRODUCTION THEREOF | KURARAY CO., LTD. (JP) | 1985-07-24 | — | — | EP | disclosed |
| EP-0054753-A1 | Polyprenyl composition or compounds and process for the production thereof | KURARAY CO., LTD. (JP) | 1982-06-30 | — | — | EP | disclosed |
| US-4025401-A | Method for diaphragm electrolysis of alkali metal halides | MARUZEN OIL CO. LTD. (JA) | 1977-05-24 | — | — | US | disclosed |
| US-4011147-A | METHOD FOR DIAPHRAGM ELECTROLYSIS OF ALKALI METAL HALIDES | MARUZEN OIL CO. LTD. (JA) | 1977-03-08 | — | — | US | disclosed |
| US-3970534-A | Graft copolymer and process for preparation thereof | MARUZEN OIL CO. LTD. (JA) | 1976-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110184173-A1 | Pyripyropene Derivatives Having An ACAT2-Inhibiting Activity | ACAT2, ACAT1, AGPAT2 | ALDH1A1 1202/4885PLK1 3302/4885SMN1; SMN2 4717/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.