Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | GLS | O94925 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL21641194 | 0.99 | TSHR (0.56) | TSHRGAARECQLKMT2AMEN1 | |
| SCHEMBL21368796 | 0.79 | GLS (0.76) | TSHRGAARECQLKMT2AMEN1 | |
| SCHEMBL15200203 | 0.77 | GLS (0.71) | TSHRGAARECQLKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL21641476 | 0.76 | KMT2A (0.65) | GAARECQLKMT2AMEN1ALDH1A1 | |
| SCHEMBL10800648 | 0.75 | ALDH1A1 (0.72) | GAARECQLKMT2AALDH1A1KDM4E | |
| SCHEMBL10800392 | 0.74 | RECQL (0.63) | TSHRGAARECQLKMT2AMEN1 | |
| SCHEMBL15727757 | 0.74 | GLS (0.67) | GAAKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL12768097 | 0.73 | TSHR (0.84) | TSHRGAARECQLKMT2AMEN1 | |
| SCHEMBL3456386 | 0.73 | RAB9A (0.66) | TSHRGAARECQLKMT2AMEN1 | |
| SCHEMBL14987417 | 0.72 | GLS (0.76) | TSHRGAAKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3604305-A1 | NOVEL PYRIDONE CARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | Wakunaga Pharmaceutical Co., Ltd. (JP) | 2020-02-05 | — | — | EP | disclosed |