Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL21640709

O=C(NCC1CCCCO1)C1(O)CNC1.O=C(O)C(F)(F)F

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.42
HTT P42858 1/20 0.42
SMN1; SMN2 Q16637 3/20 0.42
USP2 O75604 1/20 0.42
ALDH1A1 P00352 1/20 0.41
TSHR P16473 1/20 0.41
TP53 P04637 1/20 0.41
ALOX12 P18054 1/20 0.41
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
KDM4E B2RXH2 2/20 0.40
LMNA P02545 1/20 0.40
POLB P06746 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.38
MCL1 Q07820 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL21640471 0.89 HPGD (0.41) HPGDHTTSMN1; SMN2USP2ALDH1A1
SCHEMBL21640710 0.80 MEN1 (0.40) HPGDHTTSMN1; SMN2USP2ALDH1A1
Trifluoroacetic Acid SCHEMBL21641038 0.78 HPGD (0.48) HPGDHTTSMN1; SMN2USP2ALDH1A1
Hydrochloric Acid SCHEMBL21640977 0.76 TSHR (0.47) HPGDHTTSMN1; SMN2USP2ALDH1A1
Trifluoroacetic Acid SCHEMBL21641246 0.71 ALDH1A1 (0.38) HPGDHTTSMN1; SMN2ALDH1A1MEN1
Trifluoroacetic Acid SCHEMBL21640515 0.71 ALDH1A1 (0.38) HPGDHTTSMN1; SMN2ALDH1A1MEN1
Trifluoroacetic Acid SCHEMBL21640867 0.71 ALDH1A1 (0.38) HPGDHTTSMN1; SMN2ALDH1A1MEN1
SCHEMBL21640472 0.71 HPGD (0.40) HPGDHTTSMN1; SMN2USP2ALDH1A1
Trifluoroacetic Acid SCHEMBL21640588 0.70 ALDH1A1 (0.40) HPGDALDH1A1LMNAPOLB
SCHEMBL21680230 0.68 HPGD (0.53) HPGDHTTSMN1; SMN2USP2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3604305-B1 NOVEL PYRIDONE CARBOXYLIC ACID DERIVATIVE OR SALT THEREOF WAKUNAGA PHARMA CO LTD (JP) 2024-08-28 EP disclosed
US-11286255-B2 Pyridone carboxylic acid derivative or salt thereof WAKUNAGA PHARMACEUTICAL CO., LTD. (JP) 2022-03-29 US disclosed
US-20200062752-A1 NOVEL PYRIDONE CARBOXYLIC ACID DERIVATIVE OR SALT THEREOF WAKUNAGA PHARMACEUTICAL CO., LTD. (JP) 2020-02-27 US disclosed
EP-3604305-A1 NOVEL PYRIDONE CARBOXYLIC ACID DERIVATIVE OR SALT THEREOF Wakunaga Pharmaceutical Co., Ltd. (JP) 2020-02-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200062752-A1 NOVEL PYRIDONE CARBOXYLIC ACID DERIVATIVE OR SALT THEREOF RAB10, HDAC10, NEK10 HPGD 2883/4885HTT 4273/4885SMN1; SMN2 3320/4885
US-11286255-B2 Pyridone carboxylic acid derivative or salt thereof RARA, RAB10, RABL6 HPGD 2366/4885HTT 4529/4885SMN1; SMN2 3701/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.