Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ILK | Q13418 | 16/20 | 0.60 |
| ▸ | AHR | P35869 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2163642 | 0.88 | ILK (0.62) | ILKAHR | |
| SCHEMBL2164062 | 0.87 | ILK (0.62) | ILK | |
| SCHEMBL2163409 | 0.80 | ILK (0.66) | ILK | |
| SCHEMBL686429 | 0.80 | ILK (0.71) | ILK | |
| SCHEMBL13806230 | 0.75 | AHR (0.68) | ILKAHRAPP | |
| SCHEMBL686631 | 0.73 | ILK (0.71) | ILK | |
| SCHEMBL686892 | 0.72 | ILK (0.73) | ILK | |
| SCHEMBL686516 | 0.72 | ALDH1A1 (0.61) | ILK | |
| SCHEMBL687376 | 0.72 | KDM4E (0.68) | — | |
| SCHEMBL687044 | 0.70 | ILK (0.72) | ILK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110178126-A1 | PYRAZOLYLBENZOTHIAZOLE DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS | Valocor Therapeutics, Inc. (CA) | 2011-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110178126-A1 | PYRAZOLYLBENZOTHIAZOLE DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS | REN, PGF, PKD1 | ILK 1603/4885AHR 1500/4885APP 4428/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.