SCHEMBL21641579

SCHEMBL21641579

CCOCC(COCC)NC(=O)C1CN(C(=O)OC(C)(C)C)C1

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 1/20 0.42
MEN1 O00255 8/20 0.38
KMT2A Q03164 8/20 0.38
ALDH1A1 P00352 2/20 0.38
MAPT P10636 1/20 0.38
HPGD P15428 2/20 0.38
EPHX1 P07099 1/20 0.36
PTPN2 P17706 1/20 0.36
PTPN1 P18031 1/20 0.36
PTPN6 P29350 1/20 0.36
NAMPT P43490 1/20 0.36
STS P08842 1/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21640759 0.83 NR1H2 (0.49) NR1H2MEN1KMT2AALDH1A1MAPT
SCHEMBL89994 0.83 REN (0.41) NR1H2KMT2A
SCHEMBL1911486 0.83 REN (0.41) NR1H2KMT2A
SCHEMBL90236 0.83 REN (0.40) NR1H2
SCHEMBL18764776 0.74 NR1H2 (0.45) NR1H2MEN1KMT2AALDH1A1MAPT
SCHEMBL21937820 0.74 NR1H2 (0.45) NR1H2MEN1KMT2AALDH1A1MAPT
SCHEMBL21640224 0.74 NR1H2 (0.49) NR1H2MEN1KMT2AALDH1A1MAPT
SCHEMBL4330223 0.74 NR1H2 (0.49) NR1H2MEN1KMT2AALDH1A1MAPT
SCHEMBL25036399 0.73 NR1H2 (0.40) NR1H2MEN1KMT2AALDH1A1MAPT
SCHEMBL89416 0.73 NR1H2 (0.41) NR1H2MEN1KMT2AALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3604305-B1 NOVEL PYRIDONE CARBOXYLIC ACID DERIVATIVE OR SALT THEREOF WAKUNAGA PHARMA CO LTD (JP) 2024-08-28 EP disclosed
CN-110520422-B Novel pyridonecarboxylic acid derivative or salt thereof 涌永制药株式会社 2023-09-05 CN disclosed
US-11286255-B2 Pyridone carboxylic acid derivative or salt thereof WAKUNAGA PHARMACEUTICAL CO., LTD. (JP) 2022-03-29 US disclosed
US-20200062752-A1 NOVEL PYRIDONE CARBOXYLIC ACID DERIVATIVE OR SALT THEREOF WAKUNAGA PHARMACEUTICAL CO., LTD. (JP) 2020-02-27 US disclosed
EP-3604305-A1 NOVEL PYRIDONE CARBOXYLIC ACID DERIVATIVE OR SALT THEREOF Wakunaga Pharmaceutical Co., Ltd. (JP) 2020-02-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200062752-A1 NOVEL PYRIDONE CARBOXYLIC ACID DERIVATIVE OR SALT THEREOF RAB10, HDAC10, NEK10 NR1H2 876/4885MEN1 2748/4885KMT2A 2507/4885
US-11286255-B2 Pyridone carboxylic acid derivative or salt thereof RARA, RAB10, RABL6 NR1H2 675/4885MEN1 2481/4885KMT2A 2313/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.