SCHEMBL21642991

SCHEMBL21642991

N#Cc1ccc(-c2csc(C[C@H](N)C(=O)O)n2)nc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TPH1 P17752 1/20 0.45
GRM5 P41594 5/20 0.38
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
GRIK1 P39086 1/20 0.36
GRIK2 Q13002 1/20 0.36
DPP7 Q9UHL4 1/20 0.35
HSD17B10 Q99714 1/20 0.35
EGLN1 Q9GZT9 3/20 0.34
KDM4E B2RXH2 1/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
HTT P42858 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
ALPI P09923 1/20 0.33
PKM P14618 1/20 0.33
PTGS1 P23219 1/20 0.33
XIAP P98170 1/20 0.33
SLC7A5 Q01650 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21642992 1.00 TPH1 (0.45) TPH1GRM5MEN1KMT2AGRIK1
SCHEMBL21643021 0.82 TPH1 (0.39) TPH1MEN1KDM4E
SCHEMBL21643022 0.82 TPH1 (0.39) TPH1MEN1KDM4E
SCHEMBL21639405 0.78 ITGB3 (0.43)
SCHEMBL21639407 0.78 ITGB3 (0.43)
SCHEMBL21643053 0.74 USP2 (0.33) TPH1MEN1KMT2AGRIK1GRIK2
SCHEMBL21643032 0.73 USP2 (0.33) TPH1MEN1KMT2AGRIK1GRIK2
SCHEMBL21643010 0.73 USP2 (0.33) TPH1MEN1KMT2AGRIK1GRIK2
SCHEMBL21642993 0.73 EIF4E (0.34) TPH1MEN1KMT2AMAPTALPI
SCHEMBL31757442 0.71 CTSS (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11319347-B2 Peptide compound and method for producing same, composition for screening use, and method for selecting peptide compound FUJIFILM CORPORATION (JP) 2022-05-03 US disclosed
US-20200040039-A1 PEPTIDE COMPOUND AND METHOD FOR PRODUCING SAME, COMPOSITION FOR SCREENING USE, AND METHOD FOR SELECTING PEPTIDE COMPOUND FUJIFILM CORPORATION (JP) 2020-02-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200040039-A1 PEPTIDE COMPOUND AND METHOD FOR PRODUCING SAME, COMPOSITION FOR SCREENING USE, AND METHOD FOR SELECTING PEPTIDE COMPOUND VIP, NPPA, NGLY1 TPH1 4693/4885GRM5 2333/4885MEN1 329/4885
US-11319347-B2 Peptide compound and method for producing same, composition for screening use, and method for selecting peptide compound VIP, NPPA, NGLY1 TPH1 4693/4885GRM5 2333/4885MEN1 329/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.