SCHEMBL2164376

SCHEMBL2164376

N#Cc1ccccc1C([O])=O

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PPIA P62937 1/20 0.44
POLB P06746 2/20 0.44
TSHR P16473 1/20 0.43
LMNA P02545 3/20 0.42
GAA P10253 3/20 0.42
KDM4E B2RXH2 1/20 0.42
ALDH1A1 P00352 3/20 0.41
L3MBTL1 Q9Y468 2/20 0.40
HSD11B1 P28845 1/20 0.40
MAPT P10636 2/20 0.40
KAT6A Q92794 1/20 0.40
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
ESR2 Q92731 1/20 0.39
MEN1 O00255 1/20 0.39
HTT P42858 1/20 0.39
KMT2A Q03164 1/20 0.39
ALOX15 P16050 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2913776 0.84 ALDH1A1 (0.45) PPIAPOLBTSHRLMNAGAA
SCHEMBL6276445 0.84 PPIA (0.45) PPIAPOLBTSHRLMNAGAA
SCHEMBL31000747 0.84 PPIA (0.45) PPIAPOLBTSHRLMNAGAA
SCHEMBL29365220 0.82 ALDH1A1 (0.56) PPIAPOLBTSHRLMNAGAA
SCHEMBL180853 0.82 ALDH1A1 (0.56) PPIAPOLBTSHRLMNAGAA
SCHEMBL23026097 0.80 PPIA (0.43) PPIAPOLBTSHRLMNAGAA
SCHEMBL6808202 0.80 PPIA (0.43) PPIAPOLBTSHRLMNAGAA
SCHEMBL1340299 0.80 ALDH1A1 (0.48) PPIAPOLBTSHRLMNAGAA
SCHEMBL180961 0.80 ALDH1A1 (0.48) PPIAPOLBTSHRLMNAKDM4E
SCHEMBL22551097 0.80 PPIA (0.43) PPIAPOLBTSHRLMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2978852-B1 PRODUCTION OF PYRIPYROPENES FROM DRY BIOMASS BASF SE (DE) 2018-10-17 EP claimed
EP-2111756-B1 PEST CONTROL AGENTS MEIJI SEIKA PHARMA CO LTD (JP) 2017-08-02 EP claimed
EP-1889540-B9 PEST CONTROL AGENT MEIJI SEIKA PHARMA CO LTD (JP) 2012-09-26 EP claimed
EP-1889540-B1 PEST CONTROL AGENT MEIJI SEIKA PHARMA CO LTD (JP) 2011-11-02 EP claimed
US-20110184173-A1 Pyripyropene Derivatives Having An ACAT2-Inhibiting Activity THE KITASATO INSTITUTE (JP) 2011-07-28 US claimed
EP-2228376-A1 PYRIPYROPENE DERIVATIVE HAVING ACAT2-INHIBITING ACTIVITY The Kitasato Institute (JP) 2010-09-15 EP claimed
EP-2111756-A1 Pest control agents MEIJI SEIKA KAISHA LTD. (JP) 2009-10-28 EP claimed
US-7491738-B2 Pest control agents MEIJI SEIKA KAISHA, LTD. (JP) 2009-02-17 US claimed
EP-0667865-B1 OXA- AND THIADIAZOLE DERIVATIVES USED AS INSECTICIDES AND FUNGICIDES ZENECA LTD (GB) 1996-12-11 EP claimed
US-4291047-A Combating fungi with α-azolyl-β-hydroxy-ketones BAYER AKTIENGESELLSCHAFT (DE) 1981-09-22 US claimed
WO-2024135508-A1 COMPOUND, ORGANIC THIN FILM, PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, PHOTOSENSOR AND SOLID-STATE IMAGING DEVICE 三菱瓦斯化学株式会社 2024-06-27 WO disclosed
WO-2023210623-A1 HALOALKYL SULFONE ANILIDE COMPOUND AND HERBICIDE CONTAINING SAME 株式会社エス・ディー・エス バイオテック 2023-11-02 WO disclosed
WO-2023167234-A1 COMPOUND, ORGANIC THIN FILM, PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, PHOTOSENSOR AND SOLID-STATE IMAGING DEVICE 三菱瓦斯化学株式会社 2023-09-07 WO disclosed
WO-2020067144-A1 NUCLEATING AGNET, SYNTHETIC-RESIN COMPOSITION CONTAINING SAME, AND MOLDED OBJECT THEREOF 株式会社ADEKA 2020-04-02 WO disclosed
US-10150777-B2 Production of pyripyropenes from dry biomass BASF SE (DE) 2018-12-11 US disclosed
US-4533730-A BACTERICIDES SHIONOGI & CO., LTD. (JP) 1985-08-06 US disclosed
US-4504659-A 1-Oxadethiacepham compounds SHIONOGI & CO., LTD. (JP) 1985-03-12 US disclosed
US-4478997-A 1-Oxadethiacepham compounds SHIONOGI & CO., LTD. (JP) 1984-10-23 US disclosed
US-4443598-A ANTIBIOTICS AND INTERMEDIATES SHIONOGI & CO., LTD. (JP) 1984-04-17 US disclosed
US-4366316-A FROM OXAZOLINOAZETIDINONE AND ACID SHIONOGI & CO., LTD. (JP) 1982-12-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110184173-A1 Pyripyropene Derivatives Having An ACAT2-Inhibiting Activity ACAT2, ACAT1, AGPAT2 PPIA 1882/4885POLB 4043/4885TSHR 4105/4885
US-10150777-B2 Production of pyripyropenes from dry biomass CYP4F3, CYP4F2, CYP4B1 PPIA 114/4885POLB 4024/4885TSHR 1575/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.