Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.32 |
| ▸ | CDC25B | P30305 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL216446 | 0.88 | MEN1 (0.44) | MEN1KMT2AGABRA1GABRB1CA1 | |
| SCHEMBL1044854 | 0.84 | MEN1 (0.40) | MEN1KMT2AGABRA1GABRB1CA1 | |
| SCHEMBL1044852 | 0.80 | MEN1 (0.39) | MEN1KMT2AGABRA1GABRB1CA1 | |
| SCHEMBL1523966 | 0.78 | MEN1 (0.54) | MEN1KMT2AGABRA1GABRB1CA1 | |
| SCHEMBL11092448 | 0.76 | POLB (0.39) | MEN1KMT2AGABRA1GABRB1CA1 | |
| SCHEMBL11084327 | 0.75 | CA1 (0.41) | MEN1KMT2AGABRA1GABRB1CA1 | |
| SCHEMBL1048152 | 0.75 | MEN1 (0.53) | MEN1KMT2ACDC25BKDM4EALDH1A1 | |
| SCHEMBL19304039 | 0.72 | GABRA1 (0.38) | MEN1KMT2AGABRA1GABRB1CA1 | |
| SCHEMBL1048153 | 0.71 | MEN1 (0.51) | MEN1KMT2ACA1CA2KDM4E | |
| SCHEMBL1046662 | 0.70 | MEN1 (0.41) | MEN1KMT2ACDC25BKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2229353-B1 | HYDROCYANATION OF PENTENENITRILES | INVISTA TEXTILES (U K ) LTD (GB) | 2018-01-03 | — | — | EP | disclosed |
| EP-2041076-B1 | HYDROCYANATION PROCESS WITH REDUCED YIELD LOSSES | INVISTA TECH SARL (CH) | 2014-03-26 | — | — | EP | disclosed |
| US-8088943-B2 | Hydrocyanation of pentenenitriles | INVISTA NORTH AMERICA S.A R.L. (US) | 2012-01-03 | — | — | US | disclosed |
| EP-1820790-B1 | 3-alkylated-5,5',6,6',7,7',8,8'-octahydro-2,2'-binaphthols and 3,3'-dialkylated-5,5',6,6',7,7',8,8'-octahydro-2,2'-binaphthols and processes for making them | INVISTA TECH SARL (CH) | 2011-05-11 | — | — | EP | disclosed |
| EP-2279994-A1 | 3-Alkylated-5,5',6,6',7,7',8,8'-Octahydro-2,2'-Binaphthols and 3,3'-Dialkylated-5,5',6,6',7,7',8,8'-Octahydro-2,2'-Binaphthols and processes for making them | Invista Technologies S.à.r.l. (CH) | 2011-02-02 | — | — | EP | disclosed |
| EP-2275397-A1 | 3-alkylated-5,5',6,6',7,7',8,8'-octahydro-2,2'-binaphthols and 3,3'-dialkylated-5,5',6,6',7,7',8,8'-octahydro-2,2'-binaphthols and processes for making them | Invista Technologies S.à.r.l. (CH) | 2011-01-19 | — | — | EP | disclosed |
| EP-2046729-B1 | HYDROCYANATION PROCESS WITH REDUCED YIELD LOSSES | INVISTA TECH SARL (CH) | 2010-09-22 | — | — | EP | disclosed |
| EP-2229353-A1 | HYDROCYANATION OF PENTENENITRILES | Invista Technologies S.A R.L. (CH) | 2010-09-22 | — | — | EP | disclosed |
| EP-1465851-B1 | 3-ALKYLATED-5,5',6,6',7,7',8,8'-OCTAHYDRO-2,2'-BINAPHTHOLS AND 3,3'-DIALKYLATED-5,5',6,6',7,7',8,8'-OCTAHYDRO-2,2'-BINAPHTHOLS AND PROCESSES FOR MAKING THEM | INVISTA TECH SARL (CH) | 2010-06-23 | — | — | EP | disclosed |
| US-7709674-B2 | Hydrocyanation process with reduced yield losses | INVISTA NORTH AMERICA S.A R.L (US) | 2010-05-04 | — | — | US | disclosed |
| US-20090182164-A1 | HYDROCYANATION OF PENTENENITRILES | INVISTA NORTH AMERICA S.A R.L. (US) | 2009-07-16 | — | — | US | disclosed |
| EP-2041076-A2 | HYDROCYANATION PROCESS WITH REDUCED YIELD LOSSES | Invista Technologies S.a.r.l. (CH) | 2009-04-01 | — | — | EP | disclosed |
| US-20080015382-A1 | HYDROCYANATION PROCESS WITH REDUCED YIELD LOSSES | INVISTA NORTH AMERICA S.A R.L. (US) | 2008-01-17 | — | — | US | disclosed |
| WO-2008008930-A2 | HYDROCYANATION PROCESS WITH REDUCED YIELD LOSSES | INVISTA TECHNOLOGIES S.A R.L. (CH) | 2008-01-17 | — | — | WO | disclosed |
| US-20080015381-A1 | HYDROCYANATION PROCESS WITH REDUCED YIELD LOSSES | INVISTA NORTH AMERICA S.A R.L. (US) | 2008-01-17 | — | — | US | disclosed |
| EP-1820790-A2 | 3-Alkylated-5,5',6,6',7,7',8,8'-octahydro-2,2'binaphthols and 3,3'-dialkylated-5,5',6,6',7,7',8,8'-octahydro-2,2'-binaphthols and process for making them | E.I.Du pont de nemours and company (US) | 2007-08-22 | — | — | EP | disclosed |
| US-7071365-B2 | 3-alkylated-5,5′,6,6′, 7, 7′, 8, 8′—octahydro-2, 2′-binaphthols and 3, 3′-dialkylated- 5, 5′, 6, 6′, 7, 7′, 8, 8′-octahydro—2, 2′-binaphthols and processes for making | INVISTA NORTH AMERICA S.A.R.L. (US) | 2006-07-04 | — | — | US | disclosed |
| US-20050182279-A1 | 3 - Alkylated-5, 5',6, 6', 7, 7', 8, 8' - octahydro-2, 2' - binaphthols and 3, 3' - dialkylated- 5, 5', 6, 6', 7, 7', 8, 8' - octahydro - 2, 2' - binaphthols and processes for making | INVISTA NORTH AMERICA S.A.R.L. | 2005-08-18 | — | — | US | disclosed |
| US-20040054237-A1 | 3-Alkylated-5,5',6,6',7,7',8,8'-octahydro-2,2'-binaphthols and 3,3'-dialkylated- 5,5',6,6',7,7',8,8'-octahydro-2,2'-binaphthols and processes for making them | INVISTA NORTH AMERICA S.A.R.L. (F/K/A ARTEVA NORTH AMERICA S.A.R.L.) | 2004-03-18 | — | — | US | disclosed |
| US-20030100803-A1 | 3-Alkylated-5,5',6,6',7,7,'8,8'-octahydro-2,2'-binaphthols and 3,3'-dialkylated-5,5',6,6',7,7',8,8'-octahydro-2,2'-binaphthols and processes for making them | E.I. DU PONT DE NEMOURS AND COMPANY | 2003-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030100803-A1 | 3-Alkylated-5,5',6,6',7,7,'8,8'-octahydro-2,2'-binaphthols and 3,3'-dialkylated-5,5',6,6',7,7',8,8'-octahydro-2,2'-binaphthols and processes for making them | ALKBH3, ALKBH2, UGT8 | MEN1 3089/4885KMT2A 1914/4885GABRA1 1662/4885 |
| US-20090182164-A1 | HYDROCYANATION OF PENTENENITRILES | NCSTN, PNN, IDH3A | MEN1 866/4885KMT2A 2644/4885GABRA1 4685/4885 |
| US-20040054237-A1 | 3-Alkylated-5,5',6,6',7,7',8,8'-octahydro-2,2'-binaphthols and 3,3'-dialkylated- 5,5',6,6',7,7',8,8'-octahydro-2,2'-binaphthols and processes for making them | ALKBH3, ALKBH2, UGT8 | MEN1 3104/4885KMT2A 1879/4885GABRA1 1661/4885 |
| US-20050182279-A1 | 3 - Alkylated-5, 5',6, 6', 7, 7', 8, 8' - octahydro-2, 2' - binaphthols and 3, 3' - dialkylated- 5, 5', 6, 6', 7, 7', 8, 8' - octahydro - 2, 2' - binaphthols and processes for making | ALKBH3, UGT8, ALKBH2 | MEN1 2936/4885KMT2A 1953/4885GABRA1 1724/4885 |
| US-20080015382-A1 | HYDROCYANATION PROCESS WITH REDUCED YIELD LOSSES | PNN, FABP4, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | MEN1 541/4885KMT2A 1825/4885GABRA1 4531/4885 |
| US-20080015381-A1 | HYDROCYANATION PROCESS WITH REDUCED YIELD LOSSES | PNN, NIT2, NOX4 | MEN1 598/4885KMT2A 1986/4885GABRA1 3688/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.