Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Citric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 3/20 | 0.89 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Citric Acid SCHEMBL32659668 | 0.97 | CA4 (0.94) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL42945 | 0.97 | CA4 (0.94) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL22686437 | 0.97 | CA4 (0.94) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL29587574 | 0.97 | CA4 (0.94) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL1291555 | 0.97 | CA4 (0.94) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL23012792 | 0.94 | CA4 (0.89) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL8845344 | 0.94 | CA4 (0.89) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL3597963 | 0.94 | CA4 (0.89) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL21555662 | 0.94 | CA4 (0.89) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL8042141 | 0.94 | CA4 (0.89) | CA4ALDH1A1CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250092542-A1 | Co/Cd-BASED BIMETALLIC METAL-ORGANIC FRAMEWORK FOR WATER-SPLITTING | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2025-03-20 | — | — | US | claimed |
| CN-114657569-B | Ferrite compound Z-type heterojunction photo-anode film and preparation method and application thereof | 青岛理工大学 | 2023-10-20 | — | — | CN | claimed |
| CN-114471457-B | Adsorption material and preparation method and application thereof | 中国石油化工股份有限公司 | 2023-07-28 | — | — | CN | claimed |
| CN-114657569-A | Ferrite complex Z-type heterojunction photo-anode film and preparation method and application thereof | 青岛理工大学 | 2022-06-24 | — | — | CN | claimed |
| CN-114471457-A | Adsorbing material and preparation method and application thereof | 中国石油化工股份有限公司 | 2022-05-13 | — | — | CN | claimed |
| CN-111518396-B | High-ductility and high-strength polyamide material and preparation method thereof | 江门市融泰新材料科技有限公司 | 2022-03-11 | — | — | CN | claimed |
| CN-113755910-A | Cyanide-free electroplating cadmium solution with alkyl glycoside as additive component | 中国航发北京航空材料研究院 | 2021-12-07 | — | — | CN | claimed |
| CN-111518396-A | High-ductility and high-strength polyamide material and preparation method thereof | 李霞 | 2020-08-11 | — | — | CN | claimed |
| US-8173475-B2 | Method of producing photoelectric conversion device having a multilayer structure formed on a substrate | FUJIFILM CORPORATION (JP) | 2012-05-08 | — | — | US | claimed |
| US-20110186955-A1 | METHOD OF PRODUCING PHOTOELECTRIC CONVERSION DEVICE AND PHOTOELECTRIC CONVERSION DEVICE | FUJIFILM CORPORATION (JP) | 2011-08-04 | — | — | US | claimed |
| US-20110189816-A1 | METHOD OF PRODUCING PHOTOELECTRIC CONVERSION DEVICE | FUJIFILM CORPORATION (JP) | 2011-08-04 | — | — | US | claimed |
| EP-2352172-A2 | Method of producing photoelectric conversion device by liquid phase deposition | Fujifilm Corporation (JP) | 2011-08-03 | — | — | EP | claimed |
| US-12491493-B1 | Amine appended bimetallic metal-organic framework (MOF-74) for carbon dioxide capture and method of preparation thereof | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2025-12-09 | — | — | US | disclosed |
| US-12459834-B1 | Nanocomposite for wastewater treatment | IMAM MOHAMMAD IBN SAUD ISLAMIC UNIVERSITY (SA) | 2025-11-04 | — | — | US | disclosed |
| US-12453960-B1 | Nanocomposite material fabrication | IMAM MOHAMMAD IBN SAUD ISLAMIC UNIVERISTY (SA) | 2025-10-28 | — | — | US | disclosed |
| US-20250282989-A1 | SCALE INHIBITORS AND RELATED METHODS | LFS CHEMISTRY INCORPORATED (US) | 2025-09-11 | — | — | US | disclosed |
| WO-2002083167-A2 | THERAPEUTIC COMPOSITIONS FOR THE TREATMENT OF A RESPIRATORY TRACT DISEASE | UNIVERSITEIT GENT (BE) | 2002-10-24 | — | — | WO | disclosed |
| EP-0505638-B1 | Antimicrobial composition having resistance to heat and weather | HAGIWARA RESEARCH CORP (JP) | 1997-06-11 | — | — | EP | disclosed |
| US-5298252-A | Silica gel coated with metal aluminum silicate where metal has microbiocidal properties, dispersion in polymer | HAGIWARA RESEARCH CORP. (JP) | 1994-03-29 | — | — | US | disclosed |
| EP-0505638-A1 | Antimicrobial composition having resistance to heat and weather | Hagiwara Research Corporation (JP) | 1992-09-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250282989-A1 | SCALE INHIBITORS AND RELATED METHODS | NUP210, SLC6A19, SLC7A1 | CA4 522/4885ALDH1A1 4848/4885CASP1 1748/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.