Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Citric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 3/20 | 0.89 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Citric Acid SCHEMBL29496932 | 0.97 | CA4 (0.84) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL29496933 | 0.97 | CA4 (0.84) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL42945 | 0.97 | CA4 (0.94) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL29587574 | 0.97 | CA4 (0.94) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL1291555 | 0.97 | CA4 (0.94) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL22686437 | 0.97 | CA4 (0.94) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL23012792 | 0.94 | CA4 (0.89) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL20668544 | 0.94 | CA4 (0.89) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL1458270 | 0.94 | CA4 (0.89) | CA4ALDH1A1CASP1 | |
| Citric Acid SCHEMBL21555662 | 0.94 | CA4 (0.89) | CA4ALDH1A1CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250347011-A1 | BIMETALLIC RUTHENIUM-COBALT ALLOY ELECTROCATALYST FOR HYDROGEN PRODUCTION | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2025-11-13 | — | — | US | claimed |
| US-20250340433-A1 | RUTHENIUM-DOPED ALUMINA-SUPPORTED COBALT/NICKEL CATALYST FOR AMMONIA DECOMPOSITION TO HYDROGEN AND NITROGEN | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2025-11-06 | — | — | US | claimed |
| CN-109046412-B | Catalyst for preparing maleic anhydride by oxidizing n-butane and preparation method thereof | 常州新日催化剂股份有限公司 | 2021-05-25 | — | — | CN | claimed |
| US-12630488-B2 | Hydrocarbon production system, and production method and operation method thereof | OSAKA GAS CO., LTD. (JP) | 2026-05-19 | — | — | US | disclosed |
| US-12529151-B2 | Electrolysis cell unit, electrolysis cell device, hydrocarbon production system, and production method and use method of electrolysis cell unit | OSAKA GAS CO., LTD. (JP) | 2026-01-20 | — | — | US | disclosed |
| US-20250387779-A1 | METHOD FOR AMMONIA DECOMPOSITION USING CARBON MATERIAL SUPPORTED METAL CATALYST | SAUDI ARABIAN OIL CO (SA) | 2025-12-25 | — | — | US | disclosed |
| US-20250347011-A1 | BIMETALLIC RUTHENIUM-COBALT ALLOY ELECTROCATALYST FOR HYDROGEN PRODUCTION | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2025-11-13 | — | — | US | disclosed |
| US-20250340433-A1 | RUTHENIUM-DOPED ALUMINA-SUPPORTED COBALT/NICKEL CATALYST FOR AMMONIA DECOMPOSITION TO HYDROGEN AND NITROGEN | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2025-11-06 | — | — | US | disclosed |
| US-12146065-B2 | Water-based ceramic dye | CEVP SAGL (CH) | 2024-11-19 | — | — | US | disclosed |
| US-20240165592-A1 | Method for Producing Reverse Water-Gas Shift Catalyst, Reverse Water-Gas Shift Catalyst, Electrolysis Reaction System, Hydrocarbon Production System, and Method for Using Reverse Water-Gas Shift Catalyst | OSAKA GAS CO., LTD. (JP) | 2024-05-23 | — | — | US | disclosed |
| EP-4316655-A1 | METHOD FOR MANUFACTURING REVERSE WATER-GAS SHIFT CATALYST, REVERSE WATER-GAS SHIFT CATALYST, ELECTROLYTIC REACTION SYSTEM, HYDROCARBON MANUFACTURING SYSTEM, AND METHOD FOR USING REVERSE WATER-GAS SHIFT CATALYST | Osaka Gas Co., Ltd. (JP) | 2024-02-07 | — | — | EP | disclosed |
| US-20090182160-A1 | Vanadium Compositions And Methods of Making the Same | SYMYX TECHNOLOGIES, INC. (US) | 2009-07-16 | — | — | US | disclosed |
| US-20090029852-A1 | Molybdenum Compositions And Methods of Making the Same | FREESLATE, INC. | 2009-01-29 | — | — | US | disclosed |
| US-20090011930-A1 | Cerium Compositions and Methods of Making the Same | SYMYX TECHNOLOGIES, INC. (US) | 2009-01-08 | — | — | US | disclosed |
| EP-1879833-A2 | HIGH SURFACE AREA METAL AND METAL OXIDE MATERIALS AND METHODS OF MAKING SAME | Symyx Technologies, Inc. (US) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006119311-A2 | HIGH SURFACE AREA METAL AND METAL OXIDE MATERIALS AND METHODS OF MAKING SAME | SYMYX TECHNOLOGIES, INC. (US) | 2006-11-09 | — | — | WO | disclosed |
| US-5509189-A | Method for making an electrochemical cell | MASSACHUSETTS INSTITUTE OF TECHNOLOGY, A MA CORP. (US) | 1996-04-23 | — | — | US | disclosed |
| US-5403461-A | Solid electrolyte-electrode system for an electrochemical cell | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1995-04-04 | — | — | US | disclosed |
| WO-1994020997-A1 | SOLID ELECTROLYTE-ELECTRODE SYSTEM FOR AN ELECTROCHEMICAL CELL | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1994-09-15 | — | — | WO | disclosed |
| US-4962267-A | OF OLEFIN FEEDSTOCK USING A CATALYST COMPRISING RUTHENIUM OXIDE AND ALKALI METAL OXIDE | SHELL OIL COMPANY (US) | 1990-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12529151-B2 | Electrolysis cell unit, electrolysis cell device, hydrocarbon production system, and production method and use method of electrolysis cell unit | SLC9A2, EPCAM, SLC9A1 | CA4 214/4885ALDH1A1 3041/4885CASP1 868/4885 |
| US-12630488-B2 | Hydrocarbon production system, and production method and operation method thereof | HAO2, HMOX2, HMOX1 | CA4 844/4885ALDH1A1 3681/4885CASP1 2282/4885 |
| US-20250387779-A1 | METHOD FOR AMMONIA DECOMPOSITION USING CARBON MATERIAL SUPPORTED METAL CATALYST | ARG2, MT-CO2, ARG1 | CA4 792/4885ALDH1A1 4507/4885CASP1 4490/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.