Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP3 | O14638 | 4/20 | 0.50 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.50 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.46 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.39 |
| ▸ | ABL1 | P00519 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | HCK | P08631 | 2/20 | 0.39 |
| ▸ | SRC | P12931 | 2/20 | 0.39 |
| ▸ | KDR | P35968 | 2/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.39 |
| ▸ | MTOR | P42345 | 2/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.39 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.39 |
| ▸ | PRKDC | P78527 | 2/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13554542 | 1.00 | ENPP3 (0.50) | ENPP3ENPP1FGFR1FGFR4PIK3CA | |
| SCHEMBL24450111 | 0.85 | PIK3CA (0.40) | ENPP3ENPP1PIK3CAPIK3CDABL1 | |
| SCHEMBL18263905 | 0.84 | PIK3CA (0.39) | ENPP3ENPP1PIK3CAPIK3CDABL1 | |
| SCHEMBL22130298 | 0.84 | KDR (0.44) | ENPP3ENPP1PIK3CAPIK3CDABL1 | |
| SCHEMBL21292742 | 0.84 | FGFR1 (0.46) | ENPP3ENPP1FGFR1FGFR4PIK3CA | |
| SCHEMBL23347080 | 0.83 | KDR (0.39) | ENPP3ENPP1PIK3CAPIK3CDABL1 | |
| SCHEMBL25243972 | 0.81 | ACLY (0.45) | ENPP3ENPP1PIK3CAPIK3CDABL1 | |
| SCHEMBL13262981 | 0.81 | IRAK4 (0.44) | — | |
| SCHEMBL2164484 | 0.81 | GABRA1 (0.43) | ENPP3ENPP1PIK3CAPIK3CDABL1 | |
| SCHEMBL22246971 | 0.80 | ENPP3 (0.56) | ENPP3ENPP1FGFR1FGFR4SLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118373820-A | Continuous preparation method and continuous synthesis device of 5-hydroxy-7-azaindole | 峰成医药科技(天津)有限公司 | 2024-07-23 | — | — | CN | disclosed |