Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | FASN | P49327 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | LYN | P07948 | 2/20 | 0.30 |
| ▸ | BTK | Q06187 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23055267 | 0.81 | PRKCI (0.39) | PRKCITBXAS1NTRK1BRD4CREBBP | |
| SCHEMBL25124500 | 0.81 | TBXAS1 (0.40) | PRKCITBXAS1NTRK1BRD4CREBBP | |
| SCHEMBL21646360 | 0.81 | PRKCI (0.39) | PRKCITBXAS1NTRK1BRD4CREBBP | |
| SCHEMBL24629446 | 0.76 | TBXAS1 (0.43) | PRKCITBXAS1NTRK1FASNNR3C1 | |
| SCHEMBL21646359 | 0.73 | TBXAS1 (0.40) | TBXAS1EGFRBRD4CREBBPNR3C1 | |
| SCHEMBL31646996 | 0.71 | LMNA (0.39) | PRKCITBXAS1EGFRNTRK1NAMPT | |
| SCHEMBL21355616 | 0.71 | TBXAS1 (0.43) | PRKCITBXAS1BRD4CREBBPNAMPT | |
| SCHEMBL15246478 | 0.71 | TBXAS1 (0.43) | PRKCITBXAS1BRD4CREBBPNR3C1 | |
| SCHEMBL13931946 | 0.70 | QPCT (0.43) | PRKCITBXAS1EGFRBRD4CREBBP | |
| SCHEMBL17561679 | 0.70 | TBXAS1 (0.40) | PRKCITBXAS1NTRK1BRD4CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230109839-A1 | THERAPEUTIC AGENT FOR TAUOPATHIES | Sumitomo Pharma Co., Ltd. (JP) | 2023-04-13 | — | — | US | disclosed |
| WO-2020017587-A1 | PYRIDAZINONE DERIVATIVE | 大日本住友製薬株式会社 | 2020-01-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230109839-A1 | THERAPEUTIC AGENT FOR TAUOPATHIES | MAPT, PSEN1, PSEN2 | PRKCI 2534/4885TBXAS1 2785/4885EGFR 4765/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.