SCHEMBL8084797

SCHEMBL8084797

CCCOc1ccccc1OC(=O)CC

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47
AKR1C3 P42330 1/20 0.45
ALOX15 P16050 1/20 0.45
LMNA P02545 3/20 0.45
MAPT P10636 4/20 0.44
ALDH1A1 P00352 3/20 0.44
GAA P10253 2/20 0.44
PKM P14618 1/20 0.44
HTT P42858 1/20 0.44
NLRP1 Q9C000 1/20 0.44
KDM4E B2RXH2 3/20 0.44
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
RECQL P46063 1/20 0.44
NR1I2 O75469 1/20 0.44
CHRM2 P08172 1/20 0.44
CYP3A4 P08684 1/20 0.44
ADRA2A P08913 1/20 0.44
OPRK1 P41145 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8072579 0.91 CYP1A2 (0.51) AKR1C3ALOX15LMNAMAPTKDM4E
SCHEMBL8081153 0.90 LMNA (0.56) LMNAMAPTALDH1A1KDM4EMEN1
SCHEMBL8081134 0.88 LMNA (0.59) LMNAMAPTALDH1A1KDM4EMEN1
SCHEMBL8084776 0.88 LMNA (0.59) LMNAMAPTALDH1A1KDM4EMEN1
SCHEMBL11685011 0.88 KDM4E (0.44) NPC1RAB9AALOX15LMNAMAPT
SCHEMBL8435546 0.87 ALOX15 (0.55) ALOX15MAPTALDH1A1KDM4EMEN1
SCHEMBL26698283 0.86 LMNA (0.46) ALOX15LMNAMAPTALDH1A1GAA
SCHEMBL6249085 0.85 L3MBTL1 (0.59) ALOX15MAPTALDH1A1GAAKDM4E
SCHEMBL15547824 0.85 NPC1 (0.40) NPC1RAB9AALOX15LMNAMAPT
SCHEMBL9874009 0.84 LMNA (0.50) NPC1RAB9AAKR1C3LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0758013-B1 Liquid crystalline optical film, compensating film for liquid crystal display and liquid crystal display NIPPON OIL CO LTD (JP) 2000-10-11 EP disclosed
US-5855971-A Liquid crystalline optical film, compensating film for liquid crystal display comprising the liquid crystalline optical film, and liquid crystal display having the compensating film NIPPON OIL COMPANY, LIMITED (JP) 1999-01-05 US disclosed
EP-0758013-A1 Liquid crystalline optical film, compensating film for liquid crystal display and liquid crystal display NIPPON OIL COMPANY, LIMITED (JP) 1997-02-12 EP disclosed