SCHEMBL2164847

SCHEMBL2164847

O=C(O)C(O)CC1CCCCC1

nearest known ligand 0.57

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SLC1A3 P43003 3/20 0.42
SLC1A2 P43004 3/20 0.42
SLC1A1 P43005 3/20 0.42
LTA4H P09960 1/20 0.41
GRN P28799 1/20 0.41
SORT1 Q99523 1/20 0.41
METAP2 P50579 1/20 0.40
METAP1 P53582 1/20 0.40
OR51E2 Q9H255 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2164841 1.00 SLC1A3 (0.42) SLC1A3SLC1A2SLC1A1LTA4HGRN
SCHEMBL7229428 1.00 SLC1A3 (0.42) SLC1A3SLC1A2SLC1A1LTA4HGRN
SCHEMBL5981288 1.00 SLC1A3 (0.42) SLC1A3SLC1A2SLC1A1LTA4HGRN
SCHEMBL5980910 1.00 SLC1A3 (0.42) SLC1A3SLC1A2SLC1A1LTA4HGRN
SCHEMBL1931750 0.98 SLC1A3 (0.40) SLC1A3SLC1A2SLC1A1LTA4HGRN
SCHEMBL1931748 0.98 SLC1A3 (0.40) SLC1A3SLC1A2SLC1A1LTA4HGRN
SCHEMBL3353915 0.98 SLC1A3 (0.40) SLC1A3SLC1A2SLC1A1LTA4HGRN
SCHEMBL7495280 0.93 SLC1A3 (0.40) SLC1A3SLC1A2SLC1A1OR51E2
SCHEMBL3346213 0.93 SLC1A3 (0.40) SLC1A3SLC1A2SLC1A1OR51E2
SCHEMBL5981459 0.89 ALDH1A1 (0.43) LTA4HGRNSORT1METAP2METAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8530448-B2 Compounds and methods for inhibiting selectin-mediated function GLYCOMIMETICS, INC. (US) 2013-09-10 US claimed
EP-1482790-B1 PESTICIDAL COMPOSITION COMPRISING A LACTATE ESTER AS CRYSTAL GROWTH INHIBITOR MAKHTESHIM CHEM WORKS LTD (IL) 2008-08-06 EP claimed
EP-0979241-B1 (3R)-3-AMINO-4-CARBOXYBUTYRALDEHYDE DERIVATIVES INHIBITING THE RELEASE OF INTERLEUKIN-1/BETA IVAX DRUG RES INST LTD (HU) 2006-03-01 EP claimed
US-6593300-B1 Inhibitors of the interleukin-1 beta converting enzyme GYOGYSZERKUTATO INTEZET KFT. (HU) 2003-07-15 US claimed
EP-0979241-A1 (3R)-3-AMINO-4-CARBOXYBUTYRALDEHYDE DERIVATIVES INHIBITING THE RELEASE OF INTERLEUKIN-1/BETA GYOGYSZERKUTATO INTEZET KFT. (HU) 2000-02-16 EP claimed
WO-1998049189-A1 (3R)-3-AMINO-4-CARBOXYBUTYRALDEHYDE DERIVATIVES INHIBITING THE RELEASE OF INTERLEUKIN-1/BETA Gyógyszerkutató Intézet Kft. (HU) 1998-11-05 WO claimed
JP-9328692-A None JP disclosed
US-12466805-B2 Pharmaceutical compounds ALMAC DISCOVERY LIMITED (GB) 2025-11-11 US disclosed
CN-109790146-B Pharmaceutical compounds 阿尔麦克探索有限公司 2022-08-23 CN disclosed
EP-3490982-B1 PHARMACEUTICAL COMPOUNDS ALMAC DISCOVERY LTD (GB) 2022-04-20 EP disclosed
US-20220002264-A1 PHARMACEUTICAL COMPOUNDS ALMAC DISCOVERY LIMITED (GB) 2022-01-06 US disclosed
US-11174291-B2 Silstatin compounds ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2021-11-16 US disclosed
US-11053213-B2 Pharmaceutical compounds ALMAC DISCOVERY LIMITED (GB) 2021-07-06 US disclosed
EP-0836610-A1 DIGLYCOSYLATED 1,2-DIOLS AS MIMETICS OF SIALYL-LEWIS X AND SIALYL-LEWIS A Novartis AG (CH) 1998-04-22 EP disclosed
JP-H09328692-A COLORED FLAME-GENERATING LIQUID FUEL AND COLORED FLAME-GENERATING SOLID FUEL OOZEKI FUMITERU 1997-12-22 JP disclosed
EP-0629212-B1 NEW ANTICOAGULANT PEPTIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS WELL AS A PROCESS FOR THE PREPARATION THEREOF GYOGYSZERKUTATO INTEZET (HU) 1997-10-08 EP disclosed
WO-1997017363-A1 THROMBIN INHIBITORS AKZO NOBEL N.V. (NL) 1997-05-15 WO disclosed
WO-1997001569-A1 DIGLYCOSYLATED 1,2-DIOLS AS MIMETICS OF SIALYL-LEWIS X AND SIALYL-LEWIS A NOVARTIS AG (CH) 1997-01-16 WO disclosed
EP-0629212-A1 NEW ANTICOAGULANT PEPTIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS WELL AS A PROCESS FOR THE PREPARATION THEREOF. GYOGYSZERKUTATO INTEZET (HU) 1994-12-21 EP disclosed
WO-1993018060-A1 NEW ANTICOAGULANT PEPTIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS WELL AS A PROCESS FOR THE PREPARATION THEREOF Gyógyszerkutató Intézet Kft. (HU) 1993-09-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12466805-B2 Pharmaceutical compounds USP19, USP18, UBE2I SLC1A3 4309/4885SLC1A2 4518/4885SLC1A1 4147/4885
US-20220002264-A1 PHARMACEUTICAL COMPOUNDS USP19, USP18, UBE2I SLC1A3 4309/4885SLC1A2 4518/4885SLC1A1 4147/4885
US-11053213-B2 Pharmaceutical compounds USP19, USP18, UBE2I SLC1A3 4309/4885SLC1A2 4518/4885SLC1A1 4147/4885
US-11174291-B2 Silstatin compounds MSTN, CTSL, HGFAC SLC1A3 4166/4885SLC1A2 4734/4885SLC1A1 4433/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.