Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PDE5A | O76074 | 2/20 | 0.39 |
| ▸ | PRKCB | P05771 | 1/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | KLK7 | P49862 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21648521 | 1.00 | CHRNA7 (0.45) | CHRNA7ADRA1DADRA1AADRA1BPOLB | |
| SCHEMBL21648536 | 0.79 | CHRNA7 (0.42) | CHRNA7ADRA1DADRA1AADRA1BPOLB | |
| SCHEMBL21648535 | 0.79 | CHRNA7 (0.42) | CHRNA7ADRA1DADRA1AADRA1BPOLB | |
| SCHEMBL21648518 | 0.79 | CHRNA7 (0.42) | CHRNA7ADRA1DADRA1AADRA1BPOLB | |
| SCHEMBL21648557 | 0.77 | CHRNA7 (0.44) | CHRNA7ADRA1DADRA1AADRA1BPOLB | |
| SCHEMBL21648556 | 0.77 | CHRNA7 (0.44) | CHRNA7ADRA1DADRA1AADRA1BPOLB | |
| SCHEMBL24512389 | 0.75 | CHRNA7 (0.42) | CHRNA7ADRA1DADRA1AADRA1BPOLB | |
| SCHEMBL21648511 | 0.74 | PDE5A (0.39) | CHRNA7ADRA1DADRA1AADRA1BPOLB | |
| SCHEMBL14364156 | 0.73 | ADRA1D (0.51) | CHRNA7ADRA1DADRA1AADRA1BPOLB | |
| SCHEMBL14364159 | 0.72 | CHRNA7 (0.55) | CHRNA7ADRA1DADRA1AADRA1BPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220185823-A1 | Prevention, Prophylactic and Therapeutic Treatment of Autoimmune Diseases Including Multiple Sclerosis Using Novel Small Molecules and Compositions Thereof | UNIVERSITY OF SHARJAH (AE) | 2022-06-16 | — | — | US | disclosed |
| WO-2020021489-A2 | DISCOVERY OF NOVEL FIRST IN CLASS NATURE-INSPIRED COMPOUNDS TARGETING THE MITOCHONDRIAL FUNCTION AND PHARMACEUTICAL COMPOSITION THEREOF | UNIVERSITY OF SHARJAH (AE) | 2020-01-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220185823-A1 | Prevention, Prophylactic and Therapeutic Treatment of Autoimmune Diseases Including Multiple Sclerosis Using Novel Small Molecules and Compositions Thereof | HLA-DRB1, SSB, MSR1 | CHRNA7 1157/4885ADRA1D 4540/4885ADRA1A 4465/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.