Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 5/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 5/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 5/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 5/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21648557 | 1.00 | CHRNA7 (0.44) | CHRNA7MEN1KMT2AADRA1AADRA1B | |
| SCHEMBL21648528 | 0.87 | MAPKAPK2 (0.47) | ADRA1AKDM4EHPGDHTR1BHTR1D | |
| SCHEMBL21648543 | 0.87 | MAPKAPK2 (0.47) | ADRA1AKDM4EHPGDHTR1BHTR1D | |
| SCHEMBL21648544 | 0.81 | MEN1 (0.58) | MEN1KMT2AHSD17B10KDM4ETSHR | |
| SCHEMBL21648546 | 0.81 | MEN1 (0.58) | MEN1KMT2AHSD17B10KDM4ETSHR | |
| SCHEMBL21648531 | 0.81 | MEN1 (0.58) | MEN1KMT2AHSD17B10KDM4ETSHR | |
| SCHEMBL21648542 | 0.80 | CHRNA7 (0.43) | CHRNA7MEN1KMT2AADRA1AADRA1B | |
| SCHEMBL21648510 | 0.80 | CHRNA7 (0.43) | CHRNA7MEN1KMT2AADRA1AADRA1B | |
| SCHEMBL21648522 | 0.77 | CHRNA7 (0.45) | CHRNA7MEN1KMT2AADRA1AADRA1B | |
| SCHEMBL21648521 | 0.77 | CHRNA7 (0.45) | CHRNA7MEN1KMT2AADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210179605-A1 | Discovery of Novel First in Class Nature-Inspired Compounds Targeting the Mitochondrial Function and Pharmaceutical Composition Thereof | UNIVERSITY OF SHARJAH (AE) | 2021-06-17 | — | — | US | disclosed |
| WO-2020021489-A2 | DISCOVERY OF NOVEL FIRST IN CLASS NATURE-INSPIRED COMPOUNDS TARGETING THE MITOCHONDRIAL FUNCTION AND PHARMACEUTICAL COMPOSITION THEREOF | UNIVERSITY OF SHARJAH (AE) | 2020-01-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210179605-A1 | Discovery of Novel First in Class Nature-Inspired Compounds Targeting the Mitochondrial Function and Pharmaceutical Composition Thereof | NDUFAB1, TFAM, CS | CHRNA7 4876/4885MEN1 1244/4885KMT2A 4698/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.