Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3075356 | 0.86 | ALDH1A1 (0.41) | ALDH1A1ADRA2BPTGS1TDP1KDM4E | |
| SCHEMBL2940314 | 0.86 | ALDH1A1 (0.41) | ALDH1A1ADRA2BPTGS1TDP1KDM4E | |
| SCHEMBL30881973 | 0.84 | TSHR (0.39) | ALDH1A1TDP1KDM4EMAPTGAA | |
| SCHEMBL2164875 | 0.84 | TSHR (0.39) | ALDH1A1TDP1KDM4EMAPTGAA | |
| SCHEMBL10497902 | 0.84 | CD44 (0.34) | ALDH1A1ADRA2BPTGS1TDP1KDM4E | |
| SCHEMBL29017087 | 0.82 | ALDH1A1 (0.41) | ALDH1A1ADRA2BPTGS1TDP1KDM4E | |
| SCHEMBL112134 | 0.80 | ALDH1A1 (0.50) | ALDH1A1ADRA2BPTGS1TDP1KDM4E | |
| SCHEMBL29893374 | 0.80 | ALDH1A1 (0.50) | ALDH1A1ADRA2BPTGS1TDP1KDM4E | |
| Hydrochloric Acid SCHEMBL4379610 | 0.78 | ALDH1A1 (0.48) | ALDH1A1ADRA2BPTGS1TDP1KDM4E | |
| Hydrochloric Acid SCHEMBL27585317 | 0.78 | ALDH1A1 (0.48) | ALDH1A1ADRA2BPTGS1TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2150113-A1 | FUNGICIDAL COMPOSITIONS | Syngeta Participations AG (CH) | 2010-02-10 | — | — | EP | claimed |
| US-20090011935-A1 | Method of Inducing Tolerance of Plants Against Bacterioses | BASF SE (DE) | 2009-01-08 | — | — | US | claimed |
| EP-1996018-A2 | METHOD OF INDUCING TOLERANCE OF PLANTS AGAINST BACTERIOSES | BASF SE (DE) | 2008-12-03 | — | — | EP | claimed |
| WO-2008131901-A1 | FUNGICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2008-11-06 | — | — | WO | claimed |
| WO-2007104658-A2 | METHOD OF INDUCING TOLERANCE OF PLANTS AGAINST BACTERIOSES | BASF SE (DE) | 2007-09-20 | — | — | WO | claimed |
| US-9115065-B2 | Sulfonyl semicarbazides, semicarbazides and ureas, pharmaceutical compositions thereof, and methods for treating hemorrhagic fever viruses, including infections associated with Arenaviruses | Kineta, Inc. (US) | 2015-08-25 | — | — | US | disclosed |
| US-20140378681-A1 | SULFONYL SEMICARBAZIDES, SEMICARBAZIDES AND UREAS,PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS FOR TREATING HEMORRHAGIC FEVER VIRUSES, INCLUDING INFECTIONS ASSOCIATED WITH ARENAVIRUSES | SIGA TECHNOLOGIES INC. (US) | 2014-12-25 | — | — | US | disclosed |
| US-8664274-B2 | Sulfonyl semicarbazides, semicarbazides and ureas, pharmaceutical compositions thereof, and methods for treating hemorrhagic fever viruses, including infections associated with arena viruses | SIGA TECHNOLOGIES, INC. (US) | 2014-03-04 | — | — | US | disclosed |
| US-8658697-B2 | Sulfonyl semicarbazides, semicarbazides and ureas, pharmaceutical compositions thereof, and methods for treating hemorrhagic fever viruses, including infections associated with arenaviruses | SIGA TECHNOLOGIES, INC. (US) | 2014-02-25 | — | — | US | disclosed |
| US-8642596-B2 | Sulfonyl semicarbazides, semicarbazides and ureas, pharmaceutical compositions thereof, and methods for treating hemorrhagic fever viruses, including infections associated with arena viruses | SIGA TECHNOLOGIES, INC. (US) | 2014-02-04 | — | — | US | disclosed |
| US-8586617-B2 | Aminomethyl-4-imidazoles | HOFFMANN-LA ROCHE INC. (US) | 2013-11-19 | — | — | US | disclosed |
| US-20130261087-A1 | SULFONYL SEMICARBAZIDES, SEMICARBAZIDES AND UREAS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS FOR TREATING HEMORRHAGIC FEVER VIRUSES, INCLUDING INFECTIONS ASSOCIATED WITH ARENA VIRUSES | SIGA TECHNOLOGIES INC. (US) | 2013-10-03 | — | — | US | disclosed |
| US-4452628-A | TRIAZINYL BENZENE SULFONAMIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-06-05 | — | — | US | disclosed |
| EP-0023422-B1 | HERBICIDAL SULFONAMIDES, PREPARATION AND USE THEREOF, AND COMPOSITIONS CONTAINING THEM | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-02-22 | — | — | EP | disclosed |
| EP-0097013-A2 | Fungicidal heterocyclic amines | ELI LILLY AND COMPANY (US) | 1983-12-28 | — | — | EP | disclosed |
| EP-0076059-A1 | Anticoccidial combinations | ELI LILLY AND COMPANY (US) | 1983-04-06 | — | — | EP | disclosed |
| US-4366168-A | POLYETHER ANTIBIOTIC AND 2, 4-DINITRO N- 4-(POLYFLUOROALKOXY)PHENYL -6-(TRIBLUOROMETHYL) BENZENAMINE | ELI LILLY AND COMPANY (US) | 1982-12-28 | — | — | US | disclosed |
| EP-0064322-A2 | Benzenesulfonyl isocyanates, isothiocyanates, chlorides, and sulfonamides having a fluorinated substituent | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-11-10 | — | — | EP | disclosed |
| US-4304791-A | INSECTICIDES, ANTIPROTOZOA AGENTS, AND PARASITICIDES | ELI LILLY AND COMPANY (US) | 1981-12-08 | — | — | US | disclosed |
| EP-0023422-A2 | Herbicidal sulfonamides, preparation and use thereof, and compositions containing them | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-02-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090011935-A1 | Method of Inducing Tolerance of Plants Against Bacterioses | BROX, CAT, SLC11A2 | ALDH1A1 2207/4885ADRA2B 4468/4885PTGS1 262/4885 |
| US-20140378681-A1 | SULFONYL SEMICARBAZIDES, SEMICARBAZIDES AND UREAS,PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS FOR TREATING HEMORRHAGIC FEVER VIRUSES, INCLUDING INFECTIONS ASSOCIATED WITH ARENAVIRUSES | GBA1, GK, GCK | ALDH1A1 1761/4885ADRA2B 1812/4885PTGS1 4496/4885 |
| US-20130261087-A1 | SULFONYL SEMICARBAZIDES, SEMICARBAZIDES AND UREAS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS FOR TREATING HEMORRHAGIC FEVER VIRUSES, INCLUDING INFECTIONS ASSOCIATED WITH ARENA VIRUSES | SORD, GBA1, GK | ALDH1A1 3188/4885ADRA2B 2781/4885PTGS1 4279/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.