Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.34 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL342032 | 0.98 | CES1 (0.47) | CES1CES2MEN1THRBHTT | |
| SCHEMBL2925106 | 0.98 | CES1 (0.47) | CES1CES2MEN1THRBHTT | |
| SCHEMBL341903 | 0.98 | CES1 (0.47) | CES1CES2MEN1THRBHTT | |
| SCHEMBL11220391 | 0.98 | CES1 (0.47) | CES1CES2MEN1THRBHTT | |
| SCHEMBL2846235 | 0.94 | TSHR (0.38) | CES1CES2MEN1THRBHTT | |
| SCHEMBL342451 | 0.89 | FAAH (0.48) | CES1LPAR1LPAR3 | |
| SCHEMBL342453 | 0.89 | FAAH (0.48) | CES1LPAR1LPAR3 | |
| SCHEMBL2843425 | 0.85 | HSD17B10 (0.30) | — | |
| SCHEMBL21682800 | 0.80 | RAD52 (0.37) | CES1CES2RAD52NPSR1LPAR1 | |
| SCHEMBL1318668 | 0.79 | CES1 (0.48) | CES1CES2MEN1THRBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651875-B1 | AMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS | SIKA TECH AG (CH) | 2017-08-30 | — | — | EP | claimed |
| CN-103261145-B | There is the amine of secondary aliphatic amino group | SIKA TECHNOLOGY AG (CH) | 2016-04-13 | — | — | CN | claimed |
| US-9290603-B2 | Amines having secondary aliphatic amino groups | SIKA TECHNOLOGY AG (CH) | 2016-03-22 | — | — | US | claimed |
| EP-2651875-A1 | AMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS | Sika Technology AG (CH) | 2013-10-23 | — | — | EP | claimed |
| US-20130237681-A1 | AMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS | SIKA TECHNOLOGY AG (CH) | 2013-09-12 | — | — | US | claimed |
| CN-103261145-A | Amines having secondary aliphatic amino groups | SIKA TECHNOLOGY AG | 2013-08-21 | — | — | CN | claimed |
| WO-2012080264-A1 | AMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS | SIKA TECHNOLOGY AG (CH) | 2012-06-21 | — | — | WO | claimed |
| EP-2465842-A1 | Amines with secondary aliphatic amines | Sika Technology AG (CH) | 2012-06-20 | — | — | EP | claimed |
| EP-2651875-B1 | AMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS | SIKA TECH AG (CH) | 2017-08-30 | — | — | EP | disclosed |
| CN-103261145-B | There is the amine of secondary aliphatic amino group | SIKA TECHNOLOGY AG (CH) | 2016-04-13 | — | — | CN | disclosed |
| US-9290603-B2 | Amines having secondary aliphatic amino groups | SIKA TECHNOLOGY AG (CH) | 2016-03-22 | — | — | US | disclosed |
| EP-2651875-A1 | AMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS | Sika Technology AG (CH) | 2013-10-23 | — | — | EP | disclosed |
| US-20130237681-A1 | AMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS | SIKA TECHNOLOGY AG (CH) | 2013-09-12 | — | — | US | disclosed |
| CN-103261145-A | Amines having secondary aliphatic amino groups | SIKA TECHNOLOGY AG | 2013-08-21 | — | — | CN | disclosed |
| EP-1772447-A1 | Aldimines with reactive groups comprising active hydrogen, and their use | Sika Technology AG (CH) | 2007-04-11 | — | — | EP | disclosed |
| WO-2007036572-A1 | COMPOUNDS CONTAINING ALDIMINE | SIKA TECHNOLOGY AG (CH) | 2007-04-05 | — | — | WO | disclosed |
| WO-2007036574-A1 | MOISTURE-HARDENED POLYURETHANE COMPOSITIONS CONTAINING COMPOUNDS COMPRISING ALDIMINE | SIKA TECHNOLOGY AG (CH) | 2007-04-05 | — | — | WO | disclosed |
| WO-2007036571-A1 | ALDIMINES COMPRISING REACTIVE GROUPS CONTAINING ACTIVE HYDROGEN, AND USE THEREOF | SIKA TECHNOLOGY AG (CH) | 2007-04-05 | — | — | WO | disclosed |
| EP-1770107-A1 | Polyurethane composition curable by humidity | Sika Technology AG (CH) | 2007-04-04 | — | — | EP | disclosed |
| EP-1760100-A1 | Isocyanate group containing adducts and compositions having good adhesion on coated substrates | Sika Technology AG (CH) | 2007-03-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130237681-A1 | AMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS | AAAS, PNMT, PARG | CES1 4112/4885CES2 1167/4885MEN1 3165/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.