Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 5/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.48 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.42 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.42 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.42 |
| ▸ | CES1 | P23141 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL342451 | 1.00 | FAAH (0.48) | FAAHTRPV1LPAR1LPAR2LPAR3 | |
| SCHEMBL341903 | 0.91 | CES1 (0.47) | LPAR1LPAR2LPAR3CES1 | |
| SCHEMBL2925106 | 0.91 | CES1 (0.47) | LPAR1LPAR2LPAR3CES1 | |
| SCHEMBL11220391 | 0.91 | CES1 (0.47) | LPAR1LPAR2LPAR3CES1 | |
| SCHEMBL342032 | 0.91 | CES1 (0.47) | LPAR1LPAR2LPAR3CES1 | |
| SCHEMBL216493 | 0.89 | CES1 (0.44) | LPAR1LPAR3CES1 | |
| SCHEMBL2846235 | 0.84 | TSHR (0.38) | CES1 | |
| SCHEMBL17366573 | 0.82 | LPAR1 (0.47) | FAAHTRPV1LPAR1LPAR2LPAR3 | |
| SCHEMBL25762061 | 0.82 | LPAR1 (0.47) | FAAHTRPV1LPAR1LPAR2LPAR3 | |
| SCHEMBL17205377 | 0.79 | LPAR1 (0.45) | FAAHTRPV1LPAR1LPAR2LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3283550-B1 | CATALYST CONTAINING AMIDINE GROUPS | SIKA TECH AG (CH) | 2020-12-16 | — | — | EP | disclosed |
| EP-3294803-B1 | GUANIDINE GROUP CONTAINING CATALYST | SIKA TECH AG (CH) | 2020-12-09 | — | — | EP | disclosed |
| US-10414875-B2 | Catalyst containing guanidine groups | SIKA TECHNOLOGY AG (CH) | 2019-09-17 | — | — | US | disclosed |
| US-10392480-B2 | Catalyst containing amidine groups | SIKA TECHNOLOGY AG (CH) | 2019-08-27 | — | — | US | disclosed |
| US-20180171082-A1 | CATALYST CONTAINING AMIDINE GROUPS | SIKA TECHNOLOGY AG (CH) | 2018-06-21 | — | — | US | disclosed |
| US-20180148545-A1 | CATALYST CONTAINING GUANIDINE GROUPS | SIKA TECHNOLOGY AG (CH) | 2018-05-31 | — | — | US | disclosed |
| EP-3294803-A1 | CATALYST CONTAINING GUANIDINE GROUPS | Sika Technology AG (CH) | 2018-03-21 | — | — | EP | disclosed |
| EP-3283550-A1 | AMIDINE-GROUP CONTAINING CATALYST | Sika Technology AG (CH) | 2018-02-21 | — | — | EP | disclosed |
| WO-2016180840-A1 | CATALYST CONTAINING GUANIDINE GROUPS | SIKA TECHNOLOGY AG (CH) | 2016-11-17 | — | — | WO | disclosed |
| WO-2016166336-A1 | AMIDINE-GROUP CONTAINING CATALYST | SIKA TECHNOLOGY AG (CH) | 2016-10-20 | — | — | WO | disclosed |
| US-8759455-B2 | Two-stage curable composition containing a surface-deactivated polyisocyanate | SIKA TECHNOLOGY AG (CH) | 2014-06-24 | — | — | US | disclosed |
| US-20120045652-A1 | COMPOSITION CONTAINING A SURFACE-DEACTIVATED POLYISOCYANATE AND CURING IN TWO STAGES | SIKA TECHNOLOGY AG (CH) | 2012-02-23 | — | — | US | disclosed |
| EP-2414421-A1 | MOISTURE-REACTIVE POLYURETHANE COMPOSITION WITH ACCELERATED CURING ACHIEVED BY THE ACTION OF HEAT | Sika Technology AG (CH) | 2012-02-08 | — | — | EP | disclosed |
| US-20120012251-A1 | HOT CURING OR HEAT-ACTIVATED COMPOSITION CONTAINING A SURFACE-DEACTIVATED POLYISOCYANATE | SIKA TECHNOLOGY AG (CH) | 2012-01-19 | — | — | US | disclosed |
| EP-2236533-B1 | Heat curing or heat activatable composition comprising a surface deactivated polyisocyanate | SIKA TECHNOLOGY AG (CH) | 2011-11-09 | — | — | EP | disclosed |
| WO-2010112536-A1 | HOT CURING OR HEAT-ACTIVATED COMPOSITION CONTAINING A SURFACE-DEACTIVATED POLYISOCYANATE | SIKA TECHNOLOGY AG (CH) | 2010-10-07 | — | — | WO | disclosed |
| WO-2010112535-A1 | MOISTURE-REACTIVE POLYURETHANE COMPOSITION WITH ACCELERATED CURING ACHIEVED BY THE ACTION OF HEAT | SIKA TECHNOLOGY AG (CH) | 2010-10-07 | — | — | WO | disclosed |
| EP-2236535-A1 | Humidity curing polyurethane composition being accelerated by influence of heat | Sika Technology AG (CH) | 2010-10-06 | — | — | EP | disclosed |
| EP-2236533-A1 | Heat curing or heat activatable composition comprising a surface deactivated polyisocyanate | Sika Technology AG (CH) | 2010-10-06 | — | — | EP | disclosed |
| EP-2236534-A1 | Composition curable in two stages comprising a surface deactivated polyisocyanate | Sika Technology AG (CH) | 2010-10-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10414875-B2 | Catalyst containing guanidine groups | GMPS, GMNN, RNMT | FAAH 3635/4885TRPV1 4177/4885LPAR1 4468/4885 |
| US-20180148545-A1 | CATALYST CONTAINING GUANIDINE GROUPS | GMPS, RNMT, GMNN | FAAH 3704/4885TRPV1 4642/4885LPAR1 4531/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.