Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.37 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL341903 | 1.00 | CES1 (0.47) | CES1CES2MEN1THRBHTT | |
| SCHEMBL11220391 | 1.00 | CES1 (0.47) | CES1CES2MEN1THRBHTT | |
| SCHEMBL2925106 | 1.00 | CES1 (0.47) | CES1CES2MEN1THRBHTT | |
| SCHEMBL216493 | 0.98 | CES1 (0.44) | CES1CES2MEN1THRBHTT | |
| SCHEMBL2846235 | 0.92 | TSHR (0.38) | CES1CES2MEN1THRBHTT | |
| SCHEMBL342451 | 0.91 | FAAH (0.48) | CES1LPAR1LPAR3LPAR2 | |
| SCHEMBL342453 | 0.91 | FAAH (0.48) | CES1LPAR1LPAR3LPAR2 | |
| SCHEMBL2843425 | 0.83 | HSD17B10 (0.30) | — | |
| SCHEMBL21682800 | 0.82 | RAD52 (0.37) | CES1CES2RAD52NPSR1TSHR | |
| SCHEMBL1317078 | 0.82 | CES1 (0.48) | CES1CES2MEN1THRBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 143 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651875-B1 | AMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS | SIKA TECH AG (CH) | 2017-08-30 | — | — | EP | claimed |
| US-9290603-B2 | Amines having secondary aliphatic amino groups | SIKA TECHNOLOGY AG (CH) | 2016-03-22 | — | — | US | claimed |
| EP-2651875-A1 | AMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS | Sika Technology AG (CH) | 2013-10-23 | — | — | EP | claimed |
| US-20130237681-A1 | AMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS | SIKA TECHNOLOGY AG (CH) | 2013-09-12 | — | — | US | claimed |
| WO-2012080264-A1 | AMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS | SIKA TECHNOLOGY AG (CH) | 2012-06-21 | — | — | WO | claimed |
| EP-2465842-A1 | Amines with secondary aliphatic amines | Sika Technology AG (CH) | 2012-06-20 | — | — | EP | claimed |
| US-20100130674-A1 | METHOD FOR THE PRODUCTION OF POLYURETHANE COMPOSITIONS WITH A LOW ISOCYANATE MONOMER CONTENT | SIKA TECHNOLOGY AG (CH) | 2010-05-27 | — | — | US | claimed |
| EP-2132246-A1 | METHOD FOR THE PRODUCTION OF POLYURETHANE COMPOSITIONS WITH A LOW ISOCYANATE MONOMER CONTENT | Sika Technology AG (CH) | 2009-12-16 | — | — | EP | claimed |
| WO-2008116927-A1 | METHOD FOR THE PRODUCTION OF POLYURETHANE COMPOSITIONS WITH A LOW ISOCYANATE MONOMER CONTENT | SIKA TECHNOLOGY AG (CH) | 2008-10-02 | — | — | WO | claimed |
| EP-1975187-A1 | Method for manufacturing polyurethane compounds with low isocyanate-monomer content | Sika Technology AG (CH) | 2008-10-01 | — | — | EP | claimed |
| US-12516147-B2 | Aldimines and uses thereof | BOSTIK SA (FR) | 2026-01-06 | — | — | US | disclosed |
| US-12421345-B2 | Polyimines and uses thereof | BOSTIK SA (FR) | 2025-09-23 | — | — | US | disclosed |
| EP-4077273-B1 | ALDIMINES AND USES THEREOF | BOSTIK SA (FR) | 2025-04-02 | — | — | EP | disclosed |
| EP-4077446-B1 | POLYIMINES AND USES THEREOF | BOSTIK SA (FR) | 2023-08-23 | — | — | EP | disclosed |
| CN-112839917-B | Curable composition for alkaline substrates | SIKA技术股份公司 | 2023-08-08 | — | — | CN | disclosed |
| EP-1923445-A1 | Polyaldimine containing moisture curable hotmelt adhesive composition | Sika Technology AG (CH) | 2008-05-21 | — | — | EP | disclosed |
| WO-2008052999-A1 | POLYURETHANE COMPOSITION WITH GOOD INITIAL STRENGTH | SIKA TECHNOLOGY AG (CH) | 2008-05-08 | — | — | WO | disclosed |
| EP-1918314-A1 | Polyurethane composition with high green strength | Sika Technology AG (CH) | 2008-05-07 | — | — | EP | disclosed |
| EP-1876196-A1 | VOC free or low VOC polyurethane coating | Sika Technology AG (CH) | 2008-01-09 | — | — | EP | disclosed |
| WO-2008000831-A1 | VOC-FREE OR VOC-POOR POLYURETHANE COATING | SIKA TECHNOLOGY AG (CH) | 2008-01-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130237681-A1 | AMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS | AAAS, PNMT, PARG | CES1 4112/4885CES2 1167/4885MEN1 3165/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.