Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR4 | P51679 | 6/20 | 0.46 |
| ▸ | MPL | P40238 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 6/20 | 0.43 |
| ▸ | RAB9A | P51151 | 6/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21652197 | 0.84 | PIM1 (0.43) | CCR4NPC1RAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL30310815 | 0.84 | MPL (0.47) | MPLNPC1RAB9ATDP1SMN1; SMN2 | |
| SCHEMBL6229174 | 0.82 | CCR4 (0.46) | CCR4NPC1RAB9ATDP1SMN1; SMN2 | |
| SCHEMBL820516 | 0.81 | NTMT1 (0.38) | CCR4NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL18157876 | 0.78 | CCR4 (0.46) | CCR4NPC1RAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL10025209 | 0.78 | SREBF2 (0.54) | CCR4NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL4743676 | 0.76 | NPC1 (0.55) | CCR4NPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL5536800 | 0.76 | PDE10A (0.53) | MPLNPC1RAB9ATDP1SMN1; SMN2 | |
| SCHEMBL21652162 | 0.75 | KDM4E (0.51) | NPC1RAB9ASMN1; SMN2TP53KMT2A | |
| SCHEMBL21652239 | 0.75 | RAB9A (0.46) | CCR4NPC1RAB9ATP53KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10544092-B2 | Malononitrile oxime ether compound and use thereof | SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD. (CN) | 2020-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10544092-B2 | Malononitrile oxime ether compound and use thereof | ME1, MAL2, ME3 | CCR4 1089/4885MPL 3570/4885NPC1 4630/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.