Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.67 |
| ▸ | RAB9A | P51151 | 7/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.67 |
| ▸ | TP53 | P04637 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | CASP2 | P42575 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | CSNK1D | P48730 | 6/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | SCD | O00767 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9332358 | 0.81 | NPC1 (0.77) | NPC1RAB9ASMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL8353964 | 0.81 | CASP2 (0.77) | NPC1RAB9ASMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL29500248 | 0.81 | CASP2 (0.77) | NPC1RAB9ASMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL9332913 | 0.80 | CASP2 (0.79) | NPC1RAB9ASMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL20543332 | 0.79 | CASP2 (1.00) | NPC1RAB9ASMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL7786534 | 0.79 | CASP2 (0.77) | NPC1RAB9ASMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL5653636 | 0.79 | CASP2 (0.77) | NPC1RAB9ASMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL7933605 | 0.79 | CASP2 (0.77) | NPC1RAB9ASMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL9332924 | 0.78 | NPC1 (0.72) | NPC1RAB9ASMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL9333305 | 0.78 | NPC1 (0.76) | NPC1RAB9ASMN1; SMN2TP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3395795-B1 | MALONONITRILE OXIME ETHER COMPOUND AND USE THEREOF | SHENYANG SINOCHEM AGROCHEMICALS R & D CO LTD (CN) | 2023-07-19 | — | — | EP | disclosed |
| US-10544092-B2 | Malononitrile oxime ether compound and use thereof | SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD. (CN) | 2020-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10544092-B2 | Malononitrile oxime ether compound and use thereof | ME1, MAL2, ME3 | NPC1 4630/4885RAB9A 4007/4885SMN1; SMN2 1799/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.