Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 6/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.40 |
| ▸ | CPT1A | P50416 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21653278 | 0.88 | SMN1; SMN2 (0.45) | SMN1; SMN2MAPTPDE10ATP53RECQL | |
| SCHEMBL21653250 | 0.86 | ALDH1A1 (0.43) | SMN1; SMN2MAPTTP53KDM4EALDH1A1 | |
| SCHEMBL21652912 | 0.85 | KDM4E (0.45) | SMN1; SMN2MAPTPDE10AKDM4EALDH1A1 | |
| SCHEMBL21653124 | 0.85 | PPARG (0.40) | SMN1; SMN2MAPTTP53KDM4EALDH1A1 | |
| SCHEMBL21653140 | 0.84 | ALDH1A1 (0.45) | SMN1; SMN2MAPTPDE10ATP53RECQL | |
| SCHEMBL21653078 | 0.81 | USP7 (0.39) | SMN1; SMN2KDM4EALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL21653240 | 0.81 | ALDH1A1 (0.45) | SMN1; SMN2MAPTTP53KDM4EALDH1A1 | |
| SCHEMBL21653129 | 0.80 | KDM4E (0.47) | SMN1; SMN2MAPTTP53KDM4EALDH1A1 | |
| SCHEMBL21653230 | 0.79 | ALDH1A1 (0.49) | SMN1; SMN2MAPTTP53KDM4EALDH1A1 | |
| SCHEMBL21653136 | 0.78 | SMN1; SMN2 (0.47) | SMN1; SMN2MAPTPDE10ATP53RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020023657-A1 | PYRIDIN-2-ONE COMPOUNDS USEFUL AS SMARCA2 ANTAGONISTS | Epizyme, Inc. (US) | 2020-01-30 | — | — | WO | disclosed |