Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 3/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.42 |
| ▸ | FEN1 | P39748 | 3/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.39 |
| ▸ | VRK1 | Q99986 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.34 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.34 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.34 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22198980 | 0.79 | GRIN2B (0.48) | GRIN2BCYP2C19RPS6KA3DAPK3NTRK1 | |
| SCHEMBL13310783 | 0.79 | AKR1C3 (0.48) | PDE3BPDE3AFEN1ALOX5APAKR1C3 | |
| SCHEMBL13310775 | 0.78 | NISCH (0.44) | PDE3BPDE3AVRK1ABL1AKR1C3 | |
| SCHEMBL13310767 | 0.77 | PDE3B (0.48) | PDE3BPDE3AFEN1ALOX5APRPS6KA3 | |
| SCHEMBL91804 | 0.76 | AKR1C3 (0.41) | PDE3BPDE3AFEN1ALOX5APAKR1C3 | |
| SCHEMBL15243549 | 0.75 | PDE3B (0.44) | PDE3BPDE3AABL1GRIN2BGRIN1 | |
| SCHEMBL26392530 | 0.75 | RPS6KA3 (0.39) | PDE3BPDE3AFEN1ALOX5APAKR1C3 | |
| SCHEMBL13703910 | 0.71 | AKR1C3 (0.49) | PDE3BPDE3AFEN1ALOX5APAKR1C3 | |
| SCHEMBL27325025 | 0.69 | PTGS2 (0.43) | CYP3A4HSD17B1HSD17B2DAPK3NTRK1 | |
| SCHEMBL17149180 | 0.68 | ALDH1A1 (0.36) | PDE3BPDE3AVRK1GRIN2BCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10544365-B2 | Nematic liquid crystal composition | DIC CORPORATION (JP) | 2020-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10544365-B2 | Nematic liquid crystal composition | DOCK5, CDKL5, NCS1 | PDE3B 2006/4885PDE3A 1040/4885FEN1 3374/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.