Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.31 |
| ▸ | ADA | P00813 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18948524 | 1.00 | NR1I2 (0.33) | NR1I2LMNASLC2A1ADAKDR | |
| SCHEMBL20848541 | 1.00 | NR1I2 (0.33) | NR1I2LMNASLC2A1ADAKDR | |
| SCHEMBL22593005 | 0.72 | ALDH1A1 (0.34) | — | |
| SCHEMBL21217035 | 0.71 | PLA2G4A (0.36) | NR1I2 | |
| SCHEMBL18430567 | 0.71 | PLA2G4A (0.36) | NR1I2 | |
| SCHEMBL18948435 | 0.71 | PLA2G4A (0.36) | NR1I2 | |
| SCHEMBL19334597 | 0.71 | PLA2G4A (0.36) | NR1I2 | |
| SCHEMBL20098093 | 0.70 | PLA2G4A (0.35) | NR1I2 | |
| SCHEMBL21081196 | 0.70 | SMN1; SMN2 (0.38) | LMNA | |
| SCHEMBL20756396 | 0.69 | NOS1 (0.33) | NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10548317-B2 | Pesticidally active pyrazole derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2020-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10548317-B2 | Pesticidally active pyrazole derivatives | ACHE, AADAC, API5 | NR1I2 2257/4885LMNA 2858/4885SLC2A1 4849/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.