Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 6/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | HTR2B | P41595 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2168127 | 0.94 | SMN1; SMN2 (0.57) | CYP1A2CYP3A4ALDH1A1CYP2C19SMN1; SMN2 | |
| SCHEMBL2522348 | 0.86 | ALDH1A1 (0.52) | CYP1A2CYP3A4ALDH1A1CYP2C19SMN1; SMN2 | |
| SCHEMBL13747160 | 0.79 | ALDH1A1 (0.53) | CYP1A2CYP3A4ALDH1A1CYP2C19SMN1; SMN2 | |
| SCHEMBL6241465 | 0.79 | CYP1A2 (0.59) | CYP1A2CYP3A4ALDH1A1CYP2C19SMN1; SMN2 | |
| SCHEMBL3741810 | 0.79 | ALDH1A1 (0.50) | CYP1A2CYP3A4ALDH1A1CYP2C19SMN1; SMN2 | |
| SCHEMBL3741806 | 0.79 | ALDH1A1 (0.50) | CYP1A2CYP3A4ALDH1A1CYP2C19SMN1; SMN2 | |
| SCHEMBL2720506 | 0.77 | ALDH1A1 (0.70) | CYP1A2CYP3A4ALDH1A1CYP2C19SMN1; SMN2 | |
| SCHEMBL18065739 | 0.76 | ALDH1A1 (0.55) | CYP1A2CYP3A4ALDH1A1CYP2C19SMN1; SMN2 | |
| SCHEMBL12416593 | 0.76 | CYP1A2 (0.69) | CYP1A2CYP3A4ALDH1A1CYP2C19SMN1; SMN2 | |
| SCHEMBL672776 | 0.75 | CYP1A2 (0.49) | CYP1A2CYP3A4ALDH1A1CYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6346621-B1 | INDOLE OR QUINOLINE COMPOUNDS SUBSTITUTED WITH AMINO COMPOUNDS ON NITROGEN | TOSOH CORPORATION (JP) | 2002-02-12 | — | — | US | claimed |
| EP-1867623-B1 | TERPHENYLENE DERIVATIVES, TETRAHALOTERPHENYL DERIVATIVES AND PROCESSES FOR THE PRODUCTION OF BOTH | TOSOH CORP (JP) | 2017-05-10 | — | — | EP | disclosed |
| US-7985885-B2 | Terphenylene derivative, tetrahaloterphenyl derivative, and processes for producing both | TOSOH CORPORATION (JP) | 2011-07-26 | — | — | US | disclosed |
| US-20090023957-A1 | TERPHENYLENE DERIVATIVE, TETRAHALOTERPHENYL DERIVATIVE, AND PROCESSES FOR PRODUCING BOTH | TOSOH CORPORATION (JP) | 2009-01-22 | — | — | US | disclosed |
| EP-1035114-B1 | Processes for the preparation of nitrogen-heterocyclic compounds | TOSOH CORP (JP) | 2004-11-24 | — | — | EP | disclosed |
| US-6346621-B1 | INDOLE OR QUINOLINE COMPOUNDS SUBSTITUTED WITH AMINO COMPOUNDS ON NITROGEN | TOSOH CORPORATION (JP) | 2002-02-12 | — | — | US | disclosed |
| EP-1035114-A2 | Nitrogen-heterocyclic compounds and process for production thereof | TOSOH CORPORATION (JP) | 2000-09-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090023957-A1 | TERPHENYLENE DERIVATIVE, TETRAHALOTERPHENYL DERIVATIVE, AND PROCESSES FOR PRODUCING BOTH | TERT, TLN1, TTI1 | CYP1A2 343/4885CYP3A4 277/4885ALDH1A1 954/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.