Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | PGR | P06401 | 2/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2168127 | 0.92 | SMN1; SMN2 (0.57) | ALDH1A1MAPTSMN1; SMN2KDM4ENPC1 | |
| SCHEMBL2165572 | 0.86 | CYP1A2 (0.55) | ALDH1A1MAPTSMN1; SMN2KDM4ENPC1 | |
| SCHEMBL30912172 | 0.82 | SMN1; SMN2 (0.64) | ALDH1A1MAPTSMN1; SMN2KDM4ENPC1 | |
| SCHEMBL5058433 | 0.82 | SMN1; SMN2 (0.64) | ALDH1A1MAPTSMN1; SMN2KDM4ENPC1 | |
| SCHEMBL18582934 | 0.82 | SMN1; SMN2 (0.64) | ALDH1A1MAPTSMN1; SMN2KDM4ENPC1 | |
| SCHEMBL5016641 | 0.82 | SMN1; SMN2 (0.64) | ALDH1A1MAPTSMN1; SMN2KDM4ENPC1 | |
| SCHEMBL3280539 | 0.80 | SMN1; SMN2 (0.61) | ALDH1A1MAPTSMN1; SMN2KDM4ENPC1 | |
| SCHEMBL29924230 | 0.80 | SMN1; SMN2 (0.61) | ALDH1A1MAPTSMN1; SMN2KDM4ENPC1 | |
| SCHEMBL2720506 | 0.77 | ALDH1A1 (0.70) | ALDH1A1MAPTSMN1; SMN2KDM4ENPC1 | |
| Fluorene SCHEMBL31388525 | 0.76 | MAOA (0.68) | ALDH1A1MAPTSMN1; SMN2KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8039128-B2 | Fluorene compound, organic light emitting device and display device using the fluorene compound | CANON KABUSHIKI KAISHA (JP) | 2011-10-18 | — | — | US | disclosed |
| US-20100072885-A1 | FLUORENE COMPOUND, ORGANIC LIGHT EMITTING DEVICE AND DISPLAY DEVICE USING THE FLUORENE COMPOUND | CANON KABUSHIKI KAISHA (JP) | 2010-03-25 | — | — | US | disclosed |
| WO-2008146825-A1 | FLUORENE COMPOUND, ORGANIC LIGHT EMITTING DEVICE AND DISPLAY DEVICE USING THE FLUORENE COMPOUND | CANON KABUSHIKI KAISHA (JP) | 2008-12-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100072885-A1 | FLUORENE COMPOUND, ORGANIC LIGHT EMITTING DEVICE AND DISPLAY DEVICE USING THE FLUORENE COMPOUND | ARL1, AFF1, AFF2 | ALDH1A1 165/4885MAPT 3257/4885SMN1; SMN2 3419/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.