SCHEMBL21656546

SCHEMBL21656546

CCOC(=O)c1ccc(Oc2ccc(C3C4CC5CC(C4)CC3C5)cc2)nc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE4B Q07343 1/20 0.51
LMNA P02545 3/20 0.41
MAPT P10636 2/20 0.41
TSHR P16473 2/20 0.41
POLB P06746 3/20 0.39
HRH3 Q9Y5N1 1/20 0.38
OPRM1 P35372 3/20 0.38
OPRK1 P41145 3/20 0.38
KDM4E B2RXH2 1/20 0.37
KMT2A Q03164 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
MAOA P21397 1/20 0.37
P2RX3 P56373 1/20 0.37
PKM P14618 1/20 0.37
ALDH1A1 P00352 1/20 0.36
HPGD P15428 1/20 0.36
MAPK1 P28482 1/20 0.36
RECQL P46063 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23210615 1.00 PDE4B (0.51) PDE4BLMNAMAPTTSHRPOLB
SCHEMBL23210665 0.88 LMNA (0.51) PDE4BLMNATSHRPOLBHRH3
SCHEMBL23210666 0.88 LMNA (0.51) PDE4BLMNATSHRPOLBHRH3
SCHEMBL23210710 0.86 LMNA (0.48) LMNAMAPTTSHRPOLBCYP1A2
SCHEMBL23210709 0.86 LMNA (0.48) LMNAMAPTTSHRPOLBCYP1A2
SCHEMBL30417556 0.84 PDE4B (0.48) PDE4BLMNAMAPTTSHRPOLB
SCHEMBL21656694 0.84 PDE4B (0.48) PDE4BLMNAMAPTTSHRPOLB
SCHEMBL25170224 0.84 PDE4B (0.48) PDE4BLMNAMAPTTSHRPOLB
SCHEMBL23210684 0.84 MAPT (0.43) MAPTPOLBHRH3OPRM1OPRK1
SCHEMBL23210687 0.84 MAPT (0.43) MAPTPOLBHRH3OPRM1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12600696-B2 Aromatic compounds Xeniopro GmbH (DE) 2026-04-14 US disclosed
US-20230150923-A1 NOVEL AROMATIC COMPOUNDS Xeniopro GmbH (DE) 2023-05-18 US disclosed
US-11591289-B2 Aromatic compounds Xeniopro GmbH (DE) 2023-02-28 US disclosed
US-20210107863-A2 NOVEL AROMATIC COMPOUNDS Xeniopro GmbH (DE) 2021-04-15 US disclosed
US-20210107863-A2 NOVEL AROMATIC COMPOUNDS Xeniopro GmbH (DE) 2021-04-15 US disclosed
US-20200031763-A1 NOVEL AROMATIC COMPOUNDS Xeniopro GmbH (DE) 2020-01-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230150923-A1 NOVEL AROMATIC COMPOUNDS AHR, TYR, MUSK PDE4B 4605/4885LMNA 3327/4885MAPT 2272/4885
US-11591289-B2 Aromatic compounds AHR, TYR, MUSK PDE4B 4661/4885LMNA 3083/4885MAPT 2195/4885
US-20210107863-A2 NOVEL AROMATIC COMPOUNDS AHR, TYR, MUSK PDE4B 4605/4885LMNA 3327/4885MAPT 2272/4885
US-12600696-B2 Aromatic compounds CCR1, CCRL2, AHR PDE4B 4799/4885LMNA 832/4885MAPT 4404/4885
US-20200031763-A1 NOVEL AROMATIC COMPOUNDS AHR, TYR, MUSK PDE4B 4605/4885LMNA 3327/4885MAPT 2272/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.