SCHEMBL23210684

SCHEMBL23210684

O=C(O)c1ccc(Oc2ccc(C3C4CC5CC(C4)CC3C5)cc2)nc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.43
OPRM1 P35372 6/20 0.40
OPRK1 P41145 6/20 0.40
OPRD1 P41143 2/20 0.40
HRH3 Q9Y5N1 6/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
GRM2 Q14416 1/20 0.39
CYSLTR1 Q9Y271 1/20 0.39
POLB P06746 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
GABRP O00591 1/20 0.38
GABRD O14764 1/20 0.38
GABRA1 P14867 1/20 0.38
GABRB1 P18505 1/20 0.38
GABRG2 P18507 1/20 0.38
GABRB3 P28472 1/20 0.38
GABRA5 P31644 1/20 0.38
GABRA3 P34903 1/20 0.38
GABRA2 P47869 1/20 0.38
GABRB2 P47870 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23210687 1.00 MAPT (0.43) MAPTOPRM1OPRK1OPRD1HRH3
SCHEMBL21628647 0.89 OPRM1 (0.50) OPRM1OPRK1OPRD1HRH3
SCHEMBL21628648 0.89 OPRM1 (0.50) OPRM1OPRK1OPRD1HRH3
SCHEMBL21628892 0.87 POLB (0.43) OPRM1OPRK1OPRD1HRH3POLB
SCHEMBL23210665 0.87 LMNA (0.51) OPRM1OPRK1OPRD1HRH3L3MBTL1
SCHEMBL21628894 0.87 POLB (0.43) OPRM1OPRK1OPRD1HRH3POLB
SCHEMBL23210666 0.87 LMNA (0.51) OPRM1OPRK1OPRD1HRH3L3MBTL1
SCHEMBL21628508 0.86 OPRM1 (0.49) OPRM1OPRK1OPRD1HRH3POLB
SCHEMBL21628510 0.86 OPRM1 (0.49) OPRM1OPRK1OPRD1HRH3POLB
SCHEMBL21657014 0.86 SMN1; SMN2 (0.43) OPRM1OPRK1HRH3POLBSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12600696-B2 Aromatic compounds Xeniopro GmbH (DE) 2026-04-14 US disclosed
US-20230150923-A1 NOVEL AROMATIC COMPOUNDS Xeniopro GmbH (DE) 2023-05-18 US disclosed
US-20210107863-A2 NOVEL AROMATIC COMPOUNDS Xeniopro GmbH (DE) 2021-04-15 US disclosed
US-20210107863-A2 NOVEL AROMATIC COMPOUNDS Xeniopro GmbH (DE) 2021-04-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230150923-A1 NOVEL AROMATIC COMPOUNDS AHR, TYR, MUSK MAPT 2272/4885OPRM1 3978/4885OPRK1 2780/4885
US-20210107863-A2 NOVEL AROMATIC COMPOUNDS AHR, TYR, MUSK MAPT 2272/4885OPRM1 3978/4885OPRK1 2780/4885
US-12600696-B2 Aromatic compounds CCR1, CCRL2, AHR MAPT 4404/4885OPRM1 817/4885OPRK1 684/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.